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Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development.
Avgustinova A, Laudanna C, Pascual-García M, Rovira Q, Djurec M, Castellanos A, Urdiroz-Urricelqui U, Marchese D, Prats N, Van Keymeulen A, Heyn H, Vaquerizas JM, Benitah SA. Avgustinova A, et al. Among authors: rovira q. Cell Stem Cell. 2021 Oct 7;28(10):1790-1804.e8. doi: 10.1016/j.stem.2021.04.030. Epub 2021 May 18. Cell Stem Cell. 2021. PMID: 34010627 Free article.
Heterochromatin establishment during early mammalian development is regulated by pericentromeric RNA and characterized by non-repressive H3K9me3.
Burton A, Brochard V, Galan C, Ruiz-Morales ER, Rovira Q, Rodriguez-Terrones D, Kruse K, Le Gras S, Udayakumar VS, Chin HG, Eid A, Liu X, Wang C, Gao S, Pradhan S, Vaquerizas JM, Beaujean N, Jenuwein T, Torres-Padilla ME. Burton A, et al. Among authors: rovira q. Nat Cell Biol. 2020 Jul;22(7):767-778. doi: 10.1038/s41556-020-0536-6. Epub 2020 Jun 29. Nat Cell Biol. 2020. PMID: 32601371 Free PMC article.