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Page 1
Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel.
Zhang SM, Paulin CBJ, Shu H, Yagüe-Capilla M, Michel M, Marttila P, Ortis F, Bwanika HC, Dirks C, Venkatram RP, Wiita E, Jemth AS, Almlöf I, Loseva O, Hormann FM, Koolmeister T, Linde E, Lee S, Llona-Minguez S, Haraldsson M, Axelsson H, Strömberg K, Homan EJ, Scobie M, Lundbäck T, Helleday T, Rudd SG. Zhang SM, et al. Among authors: rudd sg. iScience. 2024 Jan 13;27(2):108907. doi: 10.1016/j.isci.2024.108907. eCollection 2024 Feb 16. iScience. 2024. PMID: 38318365 Free PMC article.
Development of a chemical probe against NUDT15.
Zhang SM, Desroses M, Hagenkort A, Valerie NCK, Rehling D, Carter M, Wallner O, Koolmeister T, Throup A, Jemth AS, Almlöf I, Loseva O, Lundbäck T, Axelsson H, Regmi S, Sarno A, Krämer A, Pudelko L, Bräutigam L, Rasti A, Göttmann M, Wiita E, Kutzner J, Schaller T, Kalderén C, Cázares-Körner A, Page BDG, Krimpenfort R, Eshtad S, Altun M, Rudd SG, Knapp S, Scobie M, Homan EJ, Berglund UW, Stenmark P, Helleday T. Zhang SM, et al. Among authors: rudd sg. Nat Chem Biol. 2020 Oct;16(10):1120-1128. doi: 10.1038/s41589-020-0592-z. Epub 2020 Jul 20. Nat Chem Biol. 2020. PMID: 32690945 Free PMC article.
PrimPol-A new polymerase on the block.
Rudd SG, Bianchi J, Doherty AJ. Rudd SG, et al. Mol Cell Oncol. 2014 Oct 29;1(2):e960754. doi: 10.4161/23723548.2014.960754. eCollection 2014 Apr-Jun. Mol Cell Oncol. 2014. PMID: 27308331 Free PMC article. Review.
NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir.
Zhang SM, Rehling D, Jemth AS, Throup A, Landázuri N, Almlöf I, Göttmann M, Valerie NCK, Borhade SR, Wakchaure P, Page BDG, Desroses M, Homan EJ, Scobie M, Rudd SG, Berglund UW, Söderberg-Nauclér C, Stenmark P, Helleday T. Zhang SM, et al. Among authors: rudd sg. Cell Chem Biol. 2021 Dec 16;28(12):1693-1702.e6. doi: 10.1016/j.chembiol.2021.06.001. Epub 2021 Jun 29. Cell Chem Biol. 2021. PMID: 34192523 Free article.
Drug synergy scoring using minimal dose response matrices.
Mäkelä P, Zhang SM, Rudd SG. Mäkelä P, et al. Among authors: rudd sg. BMC Res Notes. 2021 Jan 19;14(1):27. doi: 10.1186/s13104-021-05445-7. BMC Res Notes. 2021. PMID: 33468238 Free PMC article.
32 results