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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1985 1
1988 1
1991 1
1997 1
2002 1
2003 1
2006 3
2008 1
2009 1
2014 1
2017 2
2018 4
2019 1
2020 3
2021 3
2022 6
2023 4
2024 0

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33 results

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Page 1
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production.
Hooftman A, Peace CG, Ryan DG, Day EA, Yang M, McGettrick AF, Yin M, Montano EN, Huo L, Toller-Kawahisa JE, Zecchini V, Ryan TAJ, Bolado-Carrancio A, Casey AM, Prag HA, Costa ASH, De Los Santos G, Ishimori M, Wallace DJ, Venuturupalli S, Nikitopoulou E, Frizzell N, Johansson C, Von Kriegsheim A, Murphy MP, Jefferies C, Frezza C, O'Neill LAJ. Hooftman A, et al. Among authors: ryan dg. Nature. 2023 Mar;615(7952):490-498. doi: 10.1038/s41586-023-05720-6. Epub 2023 Mar 8. Nature. 2023. PMID: 36890227 Free PMC article.
Krebs Cycle Reborn in Macrophage Immunometabolism.
Ryan DG, O'Neill LAJ. Ryan DG, et al. Annu Rev Immunol. 2020 Apr 26;38:289-313. doi: 10.1146/annurev-immunol-081619-104850. Epub 2020 Jan 27. Annu Rev Immunol. 2020. PMID: 31986069 Review.
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, Kessler BM, McGettrick AF, Hughes MM, Carroll RG, Booty LM, Knatko EV, Meakin PJ, Ashford MLJ, Modis LK, Brunori G, Sévin DC, Fallon PG, Caldwell ST, Kunji ERS, Chouchani ET, Frezza C, Dinkova-Kostova AT, Hartley RC, Murphy MP, O'Neill LA. Mills EL, et al. Among authors: ryan dg. Nature. 2018 Apr 5;556(7699):113-117. doi: 10.1038/nature25986. Epub 2018 Mar 28. Nature. 2018. PMID: 29590092 Free PMC article.
Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming.
Olagnier D, Brandtoft AM, Gunderstofte C, Villadsen NL, Krapp C, Thielke AL, Laustsen A, Peri S, Hansen AL, Bonefeld L, Thyrsted J, Bruun V, Iversen MB, Lin L, Artegoitia VM, Su C, Yang L, Lin R, Balachandran S, Luo Y, Nyegaard M, Marrero B, Goldbach-Mansky R, Motwani M, Ryan DG, Fitzgerald KA, O'Neill LA, Hollensen AK, Damgaard CK, de Paoli FV, Bertram HC, Jakobsen MR, Poulsen TB, Holm CK. Olagnier D, et al. Among authors: ryan dg. Nat Commun. 2018 Aug 29;9(1):3506. doi: 10.1038/s41467-018-05861-7. Nat Commun. 2018. PMID: 30158636 Free PMC article.
Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responses.
Lundahl MLE, Mitermite M, Ryan DG, Case S, Williams NC, Yang M, Lynch RI, Lagan E, Lebre FM, Gorman AL, Stojkovic B, Bracken AP, Frezza C, Sheedy FJ, Scanlan EM, O'Neill LAJ, Gordon SV, Lavelle EC. Lundahl MLE, et al. Among authors: ryan dg. Elife. 2022 Sep 29;11:e74690. doi: 10.7554/eLife.74690. Elife. 2022. PMID: 36173104 Free PMC article.
Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2.
Early JO, Menon D, Wyse CA, Cervantes-Silva MP, Zaslona Z, Carroll RG, Palsson-McDermott EM, Angiari S, Ryan DG, Corcoran SE, Timmons G, Geiger SS, Fitzpatrick DJ, O'Connell D, Xavier RJ, Hokamp K, O'Neill LAJ, Curtis AM. Early JO, et al. Among authors: ryan dg. Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8460-E8468. doi: 10.1073/pnas.1800431115. Epub 2018 Aug 20. Proc Natl Acad Sci U S A. 2018. PMID: 30127006 Free PMC article.
Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression.
Sciacovelli M, Dugourd A, Jimenez LV, Yang M, Nikitopoulou E, Costa ASH, Tronci L, Caraffini V, Rodrigues P, Schmidt C, Ryan DG, Young T, Zecchini VR, Rossi SH, Massie C, Lohoff C, Masid M, Hatzimanikatis V, Kuppe C, Von Kriegsheim A, Kramann R, Gnanapragasam V, Warren AY, Stewart GD, Erez A, Vanharanta S, Saez-Rodriguez J, Frezza C. Sciacovelli M, et al. Among authors: ryan dg. Nat Commun. 2022 Dec 20;13(1):7830. doi: 10.1038/s41467-022-35036-4. Nat Commun. 2022. PMID: 36539415 Free PMC article.
Metabolic symbiosis in pancreatic cancer.
Ryan DG, Frezza C. Ryan DG, et al. Nat Cancer. 2022 Nov;3(11):1277-1278. doi: 10.1038/s43018-022-00454-2. Nat Cancer. 2022. PMID: 36411319 No abstract available.
33 results