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Page 1
Retromer deficiency in Tauopathy models enhances the truncation and toxicity of Tau.
Asadzadeh J, Ruchti E, Jiao W, Limoni G, MacLachlan C, Small SA, Knott G, Santa-Maria I, McCabe BD. Asadzadeh J, et al. Nat Commun. 2022 Aug 27;13(1):5049. doi: 10.1038/s41467-022-32683-5. Nat Commun. 2022. PMID: 36030267 Free PMC article.
Using these models, we interrogate the interaction of hTau with the retromer complex, an evolutionarily conserved cargo-sorting protein assembly, whose reduced activity has been associated with both Parkinson's and late onset Alzheimer's disease. We reveal that redu …
Using these models, we interrogate the interaction of hTau with the retromer complex, an evolutionarily conserved cargo-sorting protein asse …
Molecular fingerprinting by multi-locus sequence typing identifies microevolution and nosocomial transmission of Candida glabrata in Kuwait.
Asadzadeh M, Ahmad S, Al-Sweih N, Khan Z. Asadzadeh M, et al. Front Public Health. 2023 Sep 8;11:1242622. doi: 10.3389/fpubh.2023.1242622. eCollection 2023. Front Public Health. 2023. PMID: 37744513 Free PMC article.
This study performed multi-locus sequence typing (MLST) to study genotypic relatedness among clinical C. glabrata isolates in Kuwait. METHODS: Candida glabrata isolates (n = 91) cultured from 91 patients were analyzed by MLST. Repeat isolates (n = 16) from 9 patient …
This study performed multi-locus sequence typing (MLST) to study genotypic relatedness among clinical C. glabrata isolates in Kuwait. METHOD …
Molecular epidemiology and genetic characterization of SARS-CoV-2 in Kuwait: A descriptive study.
Madi N, Safar HA, Mustafa AS, Chehadeh W, Asadzadeh M, Sadeq M, Alawadhi E, Al-Muhaini A, Benthani FA. Madi N, et al. Front Microbiol. 2022 Aug 26;13:858770. doi: 10.3389/fmicb.2022.858770. eCollection 2022. Front Microbiol. 2022. PMID: 36090111 Free PMC article.
Whole-genome sequencing has identified different clades/sub-clades circulating in Kuwait, mimicking the virus's global spread. Clade 20A was dominant from February 2020 until January 2021, and then clade 20I (Alpha, V1) emerged and dominated. ...We detected several known c …
Whole-genome sequencing has identified different clades/sub-clades circulating in Kuwait, mimicking the virus's global spread. Clade …
Opportunity for breast cancer screening in limited resource countries: a literature review and implications for Iran.
Asadzadeh VF, Broeders MJ, Kiemeney LA, Verbeek AL. Asadzadeh VF, et al. Asian Pac J Cancer Prev. 2011;12(10):2467-75. Asian Pac J Cancer Prev. 2011. PMID: 22320940 Free article. Review.
Papers were reviewed and categorized as follows: necessity and adoption of screening guidelines in LRCs (n=44); pilot implementation and barriers to screening program in LRCs (n=25); knowledge and attitudes on breast cancer and screening behaviour in LRCs (n= …
Papers were reviewed and categorized as follows: necessity and adoption of screening guidelines in LRCs (n=44); pilot implementation …
Increasing prevalence, molecular characterization and antifungal drug susceptibility of serial Candida auris isolates in Kuwait.
Khan Z, Ahmad S, Al-Sweih N, Joseph L, Alfouzan W, Asadzadeh M. Khan Z, et al. PLoS One. 2018 Apr 9;13(4):e0195743. doi: 10.1371/journal.pone.0195743. eCollection 2018. PLoS One. 2018. PMID: 29630658 Free PMC article.
The 280 isolates forming pink-colored colonies on CHROMagar Candida, were identified by Vitek 2 as Candida haemulonii (n = 166), Candida utilis (n = 49), Candida kefyr (n = 45), Candida guilliermondii (n = 9), Candida famata (n = 6) and Candida …
The 280 isolates forming pink-colored colonies on CHROMagar Candida, were identified by Vitek 2 as Candida haemulonii (n = 166), Cand …
Molecular Characterization and Sterol Profiles Identify Nonsynonymous Mutations in ERG2 as a Major Mechanism Conferring Reduced Susceptibility to Amphotericin B in Candida kefyr.
Asadzadeh M, Alfouzan W, Parker JE, Meis JF, Kelly SL, Joseph L, Ahmad S. Asadzadeh M, et al. Microbiol Spectr. 2023 Aug 17;11(4):e0147423. doi: 10.1128/spectrum.01474-23. Epub 2023 Jun 26. Microbiol Spectr. 2023. PMID: 37358415 Free PMC article.
Genetic alterations in genes involved in ergosterol biosynthesis and total cell sterols were investigated among clinical Candida kefyr isolates. C. kefyr isolates (n = 81) obtained from 74 patients in Kuwait and identified by phenotypic and molecular methods were analyzed. …
Genetic alterations in genes involved in ergosterol biosynthesis and total cell sterols were investigated among clinical Candida kefyr isola …
Sensitivity and specificity assessment of DWI and ADC for the diagnosis of osteoporosis in postmenopausal patients.
Momeni M, Asadzadeh M, Mowla K, Hanafi MG, Gharibvand MM, Sahraeizadeh A. Momeni M, et al. Radiol Med. 2020 Jan;125(1):68-74. doi: 10.1007/s11547-019-01080-2. Epub 2019 Sep 17. Radiol Med. 2020. PMID: 31531809
MATERIALS AND METHODS: Sixty postmenopausal women (mean age 60.2 6.11 years) underwent both dual-energy X-ray absorptiometry (DEXA) of the spine and MRI. Results were acquired from each patient's L2 to L4, for a total of 180 lumbar vertebrae. Based on bone mineral densit …
MATERIALS AND METHODS: Sixty postmenopausal women (mean age 60.2 6.11 years) underwent both dual-energy X-ray absorptiometry (DEXA) of the …
Evaluation of Etest and MICRONAUT-AM Assay for Antifungal Susceptibility Testing of Candida auris: Underestimation of Fluconazole Resistance by MICRONAUT-AM and Overestimation of Amphotericin B Resistance by Etest.
Asadzadeh M, Ahmad S, Alfouzan W, Al-Obaid I, Spruijtenburg B, Meijer EFJ, Meis JF, Mokaddas E. Asadzadeh M, et al. Antibiotics (Basel). 2024 Sep 4;13(9):840. doi: 10.3390/antibiotics13090840. Antibiotics (Basel). 2024. PMID: 39335013 Free PMC article.
This study evaluated the AST results of C. auris against fluconazole and AMB by gradient-MIC-strip (Etest) and broth microdilution-based MICRONAUT-AM-EUCAST (MCN-AM) assays. Clinical C. auris isolates (n = 121) identified by phenotypic and molecular methods were tested. Es …
This study evaluated the AST results of C. auris against fluconazole and AMB by gradient-MIC-strip (Etest) and broth microdilution-based MIC …
Degradation of soil quality by the waste leachate in a Mediterranean semi-arid ecosystem.
Yeilagi S, Rezapour S, Asadzadeh F. Yeilagi S, et al. Sci Rep. 2021 May 31;11(1):11390. doi: 10.1038/s41598-021-90699-1. Sci Rep. 2021. PMID: 34059717 Free PMC article.
The results revealed that LAS were significantly enriched by soil salinity-sodicity indices including electrical conductivity (EC), sodium adsorption ratio (SAR), and exchangeable sodium percentage (ESP), fertility indices including total N, available P and K, organic carb …
The results revealed that LAS were significantly enriched by soil salinity-sodicity indices including electrical conductivity (EC), sodium a …
19 results