Unraveling the oral microbiome's role in Alzheimer's disease: From pathophysiology to therapeutic potential.
Rozenblum G, Ait-Aissa K, Zahran G, Alipour M, Sahyoun AM, Munkhsaikhan U, Kassan A, Ishrat T, Wang Q, Abidi AH, Kassan M.
Rozenblum G, et al. Among authors: alipour m.
Alzheimers Dement. 2025 Dec;21(12):e71011. doi: 10.1002/alz.71011.
Alzheimers Dement. 2025.
PMID: 41388822
Free PMC article.
Review.
Oral dysbiosis contributes to Alzheimer's disease (AD) by promoting neuroinflammation. Pathobionts such as Porphyromonas gingivalis, Treponema denticola, and Fusobacterium nucleatum release virulence factors that induce amyloid beta aggregation and tau hyperphosphorylation …
Oral dysbiosis contributes to Alzheimer's disease (AD) by promoting neuroinflammation. Pathobionts such as Porphyromonas gingivalis, …