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147 results

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Page 1
The 2023 report of the Lancet Countdown on health and climate change: the imperative for a health-centred response in a world facing irreversible harms.
Romanello M, Napoli CD, Green C, Kennard H, Lampard P, Scamman D, Walawender M, Ali Z, Ameli N, Ayeb-Karlsson S, Beggs PJ, Belesova K, Berrang Ford L, Bowen K, Cai W, Callaghan M, Campbell-Lendrum D, Chambers J, Cross TJ, van Daalen KR, Dalin C, Dasandi N, Dasgupta S, Davies M, Dominguez-Salas P, Dubrow R, Ebi KL, Eckelman M, Ekins P, Freyberg C, Gasparyan O, Gordon-Strachan G, Graham H, Gunther SH, Hamilton I, Hang Y, Hänninen R, Hartinger S, He K, Heidecke J, Hess JJ, Hsu SC, Jamart L, Jankin S, Jay O, Kelman I, Kiesewetter G, Kinney P, Kniveton D, Kouznetsov R, Larosa F, Lee JKW, Lemke B, Liu Y, Liu Z, Lott M, Lotto Batista M, Lowe R, Odhiambo Sewe M, Martinez-Urtaza J, Maslin M, McAllister L, McMichael C, Mi Z, Milner J, Minor K, Minx JC, Mohajeri N, Momen NC, Moradi-Lakeh M, Morrissey K, Munzert S, Murray KA, Neville T, Nilsson M, Obradovich N, O'Hare MB, Oliveira C, Oreszczyn T, Otto M, Owfi F, Pearman O, Pega F, Pershing A, Rabbaniha M, Rickman J, Robinson EJZ, Rocklöv J, Salas RN, Semenza JC, Sherman JD, Shumake-Guillemot J, Silbert G, Sofiev M, Springmann M, Stowell JD, Tabatabaei M, Taylor J, Thompson R, Tonne C, Treskova M, Trinanes JA, Wagner F, Warnecke L, Whitcombe H… See abstract for full author list ➔ Romanello M, et al. Lancet. 2023 Dec 16;402(10419):2346-2394. doi: 10.1016/S0140-6736(23)01859-7. Epub 2023 Nov 14. Lancet. 2023. PMID: 37977174 Free PMC article. Review.
THE HUMAN COSTS OF PERSISTENT INACTION: The growing threats experienced to date are early signs and symptoms of what a rapidly changing climate could mean for the health of the world's populations. With 1337 tonnes of CO(2) emitted each second, each moment of delay worsens …
THE HUMAN COSTS OF PERSISTENT INACTION: The growing threats experienced to date are early signs and symptoms of what a rapidly changing clim …
Excess of rare, inherited truncating mutations in autism.
Krumm N, Turner TN, Baker C, Vives L, Mohajeri K, Witherspoon K, Raja A, Coe BP, Stessman HA, He ZX, Leal SM, Bernier R, Eichler EE. Krumm N, et al. Nat Genet. 2015 Jun;47(6):582-8. doi: 10.1038/ng.3303. Epub 2015 May 11. Nat Genet. 2015. PMID: 25961944 Free PMC article.
A cross-disorder dosage sensitivity map of the human genome.
Collins RL, Glessner JT, Porcu E, Lepamets M, Brandon R, Lauricella C, Han L, Morley T, Niestroj LM, Ulirsch J, Everett S, Howrigan DP, Boone PM, Fu J, Karczewski KJ, Kellaris G, Lowther C, Lucente D, Mohajeri K, Nõukas M, Nuttle X, Samocha KE, Trinh M, Ullah F, Võsa U; Epi25 Consortium; Estonian Biobank Research Team; Hurles ME, Aradhya S, Davis EE, Finucane H, Gusella JF, Janze A, Katsanis N, Matyakhina L, Neale BM, Sanders D, Warren S, Hodge JC, Lal D, Ruderfer DM, Meck J, Mägi R, Esko T, Reymond A, Kutalik Z, Hakonarson H, Sunyaev S, Brand H, Talkowski ME. Collins RL, et al. Cell. 2022 Aug 4;185(16):3041-3055.e25. doi: 10.1016/j.cell.2022.06.036. Epub 2022 Aug 1. Cell. 2022. PMID: 35917817 Free PMC article.
The role of glycans in the mechanobiology of cancer.
Purushothaman A, Mohajeri M, Lele TP. Purushothaman A, et al. J Biol Chem. 2023 Mar;299(3):102935. doi: 10.1016/j.jbc.2023.102935. Epub 2023 Jan 21. J Biol Chem. 2023. PMID: 36693448 Free PMC article. Review.
Effects of vitamin E on cognitive performance during ageing and in Alzheimer's disease.
La Fata G, Weber P, Mohajeri MH. La Fata G, et al. Nutrients. 2014 Nov 28;6(12):5453-72. doi: 10.3390/nu6125453. Nutrients. 2014. PMID: 25460513 Free PMC article. Review.
Due to its antioxidant properties, the ability of vitamin E to prevent or delay cognitive decline has been tested in clinical trials in both ageing population and Alzheimer's disease (AD) patients. The difficulty in performing precise and uniform human studies is mostly re …
Due to its antioxidant properties, the ability of vitamin E to prevent or delay cognitive decline has been tested in clinical trials in both …
Potential Links between Impaired One-Carbon Metabolism Due to Polymorphisms, Inadequate B-Vitamin Status, and the Development of Alzheimer's Disease.
Troesch B, Weber P, Mohajeri MH. Troesch B, et al. Nutrients. 2016 Dec 10;8(12):803. doi: 10.3390/nu8120803. Nutrients. 2016. PMID: 27973419 Free PMC article. Review.
Alzheimer's disease (AD) is the major cause of dementia and no preventive or effective treatment has been established to date. ...
Alzheimer's disease (AD) is the major cause of dementia and no preventive or effective treatment has been established to date. ...
Glucocorticoid-related genetic susceptibility for Alzheimer's disease.
de Quervain DJ, Poirier R, Wollmer MA, Grimaldi LM, Tsolaki M, Streffer JR, Hock C, Nitsch RM, Mohajeri MH, Papassotiropoulos A. de Quervain DJ, et al. Hum Mol Genet. 2004 Jan 1;13(1):47-52. doi: 10.1093/hmg/ddg361. Epub 2003 Oct 28. Hum Mol Genet. 2004. PMID: 14583441 Free article.
Because glucocorticoid excess increases neuronal vulnerability, genetic variations in the glucocorticoid system may be related to the risk for Alzheimer's disease (AD). We analyzed single-nucleotide polymorphisms in 10 glucocorticoid-related genes in a population of 814 AD …
Because glucocorticoid excess increases neuronal vulnerability, genetic variations in the glucocorticoid system may be related to the risk f …
Genetic testing in monogenic early-onset atrial fibrillation.
Chalazan B, Freeth E, Mohajeri A, Ramanathan K, Bennett M, Walia J, Halperin L, Roston T, Lazarte J, Hegele RA, Lehman A, Laksman Z. Chalazan B, et al. Eur J Hum Genet. 2023 Jul;31(7):769-775. doi: 10.1038/s41431-023-01383-z. Epub 2023 May 22. Eur J Hum Genet. 2023. PMID: 37217627 Free PMC article.
Variants from exome sequencing in affected individuals were filtered in a multi-step process, prior to undergoing clinical classification using current ACMG/AMP guidelines. 200 AF individuals were recruited from St. Paul's Hospital and London Health Sciences Centre who wer …
Variants from exome sequencing in affected individuals were filtered in a multi-step process, prior to undergoing clinical classification us …
147 results