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Page 1
Repotrectinib in ROS1 Fusion-Positive Non-Small-Cell Lung Cancer.
Drilon A, Camidge DR, Lin JJ, Kim SW, Solomon BJ, Dziadziuszko R, Besse B, Goto K, de Langen AJ, Wolf J, Lee KH, Popat S, Springfeld C, Nagasaka M, Felip E, Yang N, Velcheti V, Lu S, Kao S, Dooms C, Krebs MG, Yao W, Beg MS, Hu X, Moro-Sibilot D, Cheema P, Stopatschinskaja S, Mehta M, Trone D, Graber A, Sims G, Yuan Y, Cho BC; TRIDENT-1 Investigators. Drilon A, et al. N Engl J Med. 2024 Jan 11;390(2):118-131. doi: 10.1056/NEJMoa2302299. N Engl J Med. 2024. PMID: 38197815 Free PMC article. Clinical Trial.
Final Report of a Trial of Intensive versus Standard Blood-Pressure Control.
SPRINT Research Group; Lewis CE, Fine LJ, Beddhu S, Cheung AK, Cushman WC, Cutler JA, Evans GW, Johnson KC, Kitzman DW, Oparil S, Rahman M, Reboussin DM, Rocco MV, Sink KM, Snyder JK, Whelton PK, Williamson JD, Wright JT Jr, Ambrosius WT. SPRINT Research Group, et al. N Engl J Med. 2021 May 20;384(20):1921-1930. doi: 10.1056/NEJMoa1901281. N Engl J Med. 2021. PMID: 34010531 Free PMC article. Clinical Trial.
Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk.
Das Pradhan A, Glynn RJ, Fruchart JC, MacFadyen JG, Zaharris ES, Everett BM, Campbell SE, Oshima R, Amarenco P, Blom DJ, Brinton EA, Eckel RH, Elam MB, Felicio JS, Ginsberg HN, Goudev A, Ishibashi S, Joseph J, Kodama T, Koenig W, Leiter LA, Lorenzatti AJ, Mankovsky B, Marx N, Nordestgaard BG, Páll D, Ray KK, Santos RD, Soran H, Susekov A, Tendera M, Yokote K, Paynter NP, Buring JE, Libby P, Ridker PM; PROMINENT Investigators. Das Pradhan A, et al. N Engl J Med. 2022 Nov 24;387(21):1923-1934. doi: 10.1056/NEJMoa2210645. Epub 2022 Nov 5. N Engl J Med. 2022. PMID: 36342113 Clinical Trial.
Ultrafast Au(III)-Mediated Arylation of Cysteine.
Doud EA, Tilden JAR, Treacy JW, Chao EY, Montgomery HR, Kunkel GE, Olivares EJ, Adhami N, Kerr TA, Chen Y, Rheingold AL, Loo JA, Frost CG, Houk KN, Maynard HD, Spokoyny AM. Doud EA, et al. J Am Chem Soc. 2024 May 8;146(18):12365-12374. doi: 10.1021/jacs.3c12170. Epub 2024 Apr 24. J Am Chem Soc. 2024. PMID: 38656163 Free PMC article.
An oral heme oxygenase inhibitor targets immunosuppressive perivascular macrophages in preclinical models of cancer.
Bahri M, Al-Adhami T, Demirel E, Sarkar J, Feehan KT, Anstee JE, Cheung TS, Sosnowska D, Woodman CA, Macmorland W, Yang DD, Rosekilly J, Gitsaki-Taylor R, Gillett CE, Scudamore CL, Spicer J, Rahman KM, Arnold JN. Bahri M, et al. Sci Transl Med. 2025 Aug 6;17(810):eads3085. doi: 10.1126/scitranslmed.ads3085. Epub 2025 Aug 6. Sci Transl Med. 2025. PMID: 40768602 Free PMC article.
Proproliferative function of adaptor protein GRB10 in prostate carcinoma.
Khan MI, Al Johani A, Hamid A, Ateeq B, Manzar N, Adhami VM, Lall RK, Rath S, Sechi M, Siddiqui IA, Choudhry H, Zamzami MA, Havighurst TC, Huang W, Ntambi JM, Mukhtar H. Khan MI, et al. FASEB J. 2019 Mar;33(3):3198-3211. doi: 10.1096/fj.201800265RR. Epub 2018 Oct 31. FASEB J. 2019. PMID: 30379590 Free PMC article.
I., Al Johani, A., Hamid, A., Ateeq, B., Manzar, N., Adhami, V. M., Lall, R. K., Rath, S., Sechi, M., Siddiqui, I. A., Choudhry, H., Zamzami, M. ...
I., Al Johani, A., Hamid, A., Ateeq, B., Manzar, N., Adhami, V. M., Lall, R. K., Rath, S., Sechi, M., Siddiqui, I. A., …
Inhaled Fluticasone Furoate for Outpatient Treatment of Covid-19.
Boulware DR, Lindsell CJ, Stewart TG, Hernandez AF, Collins S, McCarthy MW, Jayaweera D, Gentile N, Castro M, Sulkowski M, McTigue K, Felker GM, Ginde AA, Dunsmore SE, Adam SJ, DeLong A, Hanna G, Remaly A, Thicklin F, Wilder R, Wilson S, Shenkman E, Naggie S; ACTIV-6 Study Group and Investigators. Boulware DR, et al. N Engl J Med. 2023 Sep 21;389(12):1085-1095. doi: 10.1056/NEJMoa2209421. N Engl J Med. 2023. PMID: 37733308 Free PMC article. Clinical Trial.
Assessment of leachables and extractables in "super-swelling" hydrogel-forming microarray patches.
Anjani QK, McKenna PE, Larrañeta E, Manesiotis P, Luo Y, Adhami M, Volpe-Zanutto F, Orr G, Roussel S, Donnelly RF. Anjani QK, et al. Drug Deliv Transl Res. 2025 May 31. doi: 10.1007/s13346-025-01880-2. Online ahead of print. Drug Deliv Transl Res. 2025. PMID: 40450126
This study assessed the leachable and extractable compounds from hydrogel-forming MAPs composed of Gantrez() S-97, PEG 10,000, and sodium carbonate under various conditions. Under physiological conditions (37C in water), minimal PEG 10,000 leaching (10.4 2.0%) and negligib …
This study assessed the leachable and extractable compounds from hydrogel-forming MAPs composed of Gantrez() S-97, PEG 10,000, and so …
19 results