Cortical Single-Cell Primers of Abnormal Brain Activity in Parkinson's Disease.
Mirzac D, Glaser MB, Kreis SL, Ringel F, Bange M, Herz DM, Groppa S, Rotaru L, Almeida V, Blech J, Oshaghi M, Kunz S, Klein M, Paulsen J, Luhmann HJ, Bopp T, de Jager PL, Groppa S, Gonzalez-Escamilla G.
Mirzac D, et al.
Research (Wash D C). 2025 Sep 11;8:0863. doi: 10.34133/research.0863. eCollection 2025.
Research (Wash D C). 2025.
PMID: 40948939
Free PMC article.
Abnormal brain oscillatory activity is a well-established hallmark of bradykinesia and motor impairment in Parkinson's disease (PD), yet its molecular underpinnings remain unclear. To address this gap, we analyzed over 100,000 single-cell RNA transcriptomes from fresh dors …
Abnormal brain oscillatory activity is a well-established hallmark of bradykinesia and motor impairment in Parkinson's disease (PD), …