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Page 1
Roles of estrogen receptor-alpha in mediating life span: the hypothalamic deregulation hypothesis.
Gouw AM, Efe G, Barakat R, Preecha A, Mehdizadeh M, Garan SA, Brooks GA. Gouw AM, et al. Physiol Genomics. 2017 Feb 1;49(2):88-95. doi: 10.1152/physiolgenomics.00073.2016. Epub 2016 Dec 23. Physiol Genomics. 2017. PMID: 28011880 Free article. Review.
This review paper seeks to characterize the downstream effects of ER-alpha in the hypothalamus and limbic system that affect normal endocrine functioning....
This review paper seeks to characterize the downstream effects of ER-alpha in the hypothalamus and limbic system that affect normal e …
MicroRNAs and Long Non-Coding RNAs Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on RNA-Binding Proteins.
Hashemi M, Shafiei Asheghabadi P, Moassesfar M, Mashhadikhan S, Nasirzade S, Vasheghani Farahani A, Mehdizadeh S, Minaei S, Rahmani M, Jamshidian F, Farahani N, Reiter RJ, Taheriazam A, Hasani Sadi F, Hushmandi K, Alimohammadi M, Rahimzadeh P, Entezari M. Hashemi M, et al. Mol Neurobiol. 2026 Jan 6;63(1):343. doi: 10.1007/s12035-025-05510-3. Mol Neurobiol. 2026. PMID: 41493706 Review.
Neurodegenerative diseases (NDs), including Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and Huntington's disease (HD), are marked by progressive neuronal loss and aberrant protein aggregation, presenting substantia …
Neurodegenerative diseases (NDs), including Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis …
Action mechanisms of n-3 polyunsaturated fatty acids on the oocyte maturation and developmental competence: Potential advantages and disadvantages.
Zarezadeh R, Mehdizadeh A, Leroy JLMR, Nouri M, Fayezi S, Darabi M. Zarezadeh R, et al. J Cell Physiol. 2019 Feb;234(2):1016-1029. doi: 10.1002/jcp.27101. Epub 2018 Aug 2. J Cell Physiol. 2019. PMID: 30073662 Review.
Fatty acid content of the follicular microenvironment can affect oocyte maturation and the subsequent developmental competence. Saturated and monounsaturated fatty acids are mainly used by follicle components as primary energy sources whereas polyunsaturated fatty acids (P …
Fatty acid content of the follicular microenvironment can affect oocyte maturation and the subsequent developmental competence. Satur …
Potential toxicity of nanoparticles on the reproductive system animal models: A review.
Ajdary M, Keyhanfar F, Moosavi MA, Shabani R, Mehdizadeh M, Varma RS. Ajdary M, et al. J Reprod Immunol. 2021 Nov;148:103384. doi: 10.1016/j.jri.2021.103384. Epub 2021 Sep 16. J Reprod Immunol. 2021. PMID: 34583090 Review.
Therefore, understanding how nanoparticles affect the reproductive system is of very importance. In several studies, the nanoparticle toxicity effect on the genital organs has been investigated at the clinical and molecular levels using the in vivo and in vitro models. ...
Therefore, understanding how nanoparticles affect the reproductive system is of very importance. In several studies, the nanoparticle …
Psychometric features of brief pain inventory for Parkinson's disease during medication states.
Taghizadeh G, Martinez-Martin P, Habibi SAH, Goudarzi S, Meimandi M, Dehmiyani A, Nodehi Z, Rostami S, Haji Alizadeh N, Mehdizadeh M. Taghizadeh G, et al. Disabil Rehabil. 2022 Nov;44(23):7277-7282. doi: 10.1080/09638288.2021.1977858. Epub 2021 Sep 27. Disabil Rehabil. 2022. PMID: 34570664
METHODS: We recruited 460 patients with PD and 100 non-PD controls. The pain was assessed by the BPI, King's Parkinson's disease Pain Scale (KPPS), Neuropathic Pain Symptom Inventory (NPSI), Visual Analogue Scale-Pain (VAS-pain), and short-form McGill Pain Questionn …
METHODS: We recruited 460 patients with PD and 100 non-PD controls. The pain was assessed by the BPI, King's Parkinson's disea …
PlGF knockdown induced apoptosis through Wnt signaling pathway in gastric cancer stem cells.
Akrami H, Mehdizadeh K, Moradi B, Borzabadi Farahani D, Mansouri K, Ghalib Ibraheem Alnajar S. Akrami H, et al. J Cell Biochem. 2019 Mar;120(3):3268-3276. doi: 10.1002/jcb.27593. Epub 2018 Sep 11. J Cell Biochem. 2019. PMID: 30203564
Our investigation revealed that the PlGF knockdown with PlGF-specific small interfering RNA at 40 pmol for GCSCs derived from MKN-45 and AGS at 24 hours can significantly affect the cell viability, the Wnt signaling pathway, and the apoptosis-related genes expression. ...
Our investigation revealed that the PlGF knockdown with PlGF-specific small interfering RNA at 40 pmol for GCSCs derived from MKN-45 and AGS …
Autophagy modulation effect on homotypic transfer of intracellular components via tunneling nanotubes in mesenchymal stem cells.
Sadeghsoltani F, Avci ÇB, Hassanpour P, Haiaty S, Rahmati M, Mota A, Rahbarghazi R, Nemati M, Mahdipour M, Talebi M, Takanlou LS, Takanlou MS, Mehdizadeh A. Sadeghsoltani F, et al. Stem Cell Res Ther. 2024 Jul 2;15(1):189. doi: 10.1186/s13287-024-03813-1. Stem Cell Res Ther. 2024. PMID: 38956646 Free PMC article.
How and by which mechanism autophagy modulation can affect the juxtacrine interaction of MSCs should be addressed. Here, the role of autophagy was investigated in the formation of tunneling nanotubes (TNTs) and homotypic mitochondrial donation. ...We found that the inhibit …
How and by which mechanism autophagy modulation can affect the juxtacrine interaction of MSCs should be addressed. Here, the role of …
BDNF modifies hippocampal KCC2 and NKCC1 expression in a temporal lobe epilepsy model.
Eftekhari S, Mehrabi S, Soleimani M, Hassanzadeh G, Shahrokhi A, Mostafavi H, Hayat P, Barati M, Mehdizadeh H, Rahmanzadeh R, Hadjighassem MR, Joghataei MT. Eftekhari S, et al. Acta Neurobiol Exp (Wars). 2014;74(3):276-87. doi: 10.55782/ane-2014-1993. Acta Neurobiol Exp (Wars). 2014. PMID: 25231847 Free article.
In the present study, we evaluated whether BDNF administration can affect KCC2/NKCC1 expression, ictogenesis and behavioral alterations in this paradigm. ...
In the present study, we evaluated whether BDNF administration can affect KCC2/NKCC1 expression, ictogenesis and behavioral alteratio …
Disruption of Interneuron Neurogenesis in Premature Newborns and Reversal with Estrogen Treatment.
Tibrewal M, Cheng B, Dohare P, Hu F, Mehdizadeh R, Wang P, Zheng D, Ungvari Z, Ballabh P. Tibrewal M, et al. J Neurosci. 2018 Jan 31;38(5):1100-1113. doi: 10.1523/JNEUROSCI.1875-17.2017. Epub 2017 Dec 15. J Neurosci. 2018. PMID: 29246927 Free PMC article.
Simulation of hypoxia by dimethyloxalylglycine treatment did not affect the number of interneuronal progenitors. However, estrogen treatment reduced the density of total and proliferating Nkx2.1(+) and Dlx2(+) cells in the MGEs and enhanced Ascl1 transcription factor. Estr …
Simulation of hypoxia by dimethyloxalylglycine treatment did not affect the number of interneuronal progenitors. However, estrogen tr …
Anxiety and cognitive load affect upper limb motor control in Parkinson's disease during medication phases.
Nodehi Z, Mehdizadeh H, Azad A, Mehdizadeh M, Reyhanian E, Saberi ZS, Meimandi M, Soltanzadeh A, Roohi-Azizi M, Vasaghi-Gharamaleki B, Parnianpour M, Khalaf K, Taghizadeh G. Nodehi Z, et al. Ann N Y Acad Sci. 2021 Jun;1494(1):44-58. doi: 10.1111/nyas.14564. Epub 2021 Jan 21. Ann N Y Acad Sci. 2021. PMID: 33476067
Anxiety is among the most debilitating nonmotor symptoms of Parkinson's disease (PD). This study aimed to determine how PD patients with low and high levels of anxiety (LA-PD and HA-PD, respectively) compare with age- and sex-matched controls at the level of motor control …
Anxiety is among the most debilitating nonmotor symptoms of Parkinson's disease (PD). This study aimed to determine how PD patients w …
24 results