Isovitexin, a natural adiponectin agonist, prevents glucocorticoid-induced osteosarcopenia.
Kulkarni C, Kumar S, Khatoon S, Sadhukhan S, Washimkar KR, Kumar A, Sharma S, Rajput S, Porwal K, Mugale MN, Rath SK, Godbole MM, Sanyal S, Kumar N, Mithal A, Chattopadhyay N.
Kulkarni C, et al. Among authors: kumar s.
Endocrine. 2025 Aug;89(2):565-577. doi: 10.1007/s12020-025-04251-6. Epub 2025 May 14.
Endocrine. 2025.
PMID: 40369296
METHODS: A rat model of MP-induced osteoporosis was developed to evaluate isovitexin's effects on bone health, including bone mass & microarchitecture (MicroCT), turnover markers (P1NP and CTX-1), strength (three-point bending, and nanoindentation), and quality (FTIR). …
METHODS: A rat model of MP-induced osteoporosis was developed to evaluate isovitexin's effects on bone health, including bone mass &a …