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Page 1
The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors.
Willingham SB, Volkmer JP, Gentles AJ, Sahoo D, Dalerba P, Mitra SS, Wang J, Contreras-Trujillo H, Martin R, Cohen JD, Lovelace P, Scheeren FA, Chao MP, Weiskopf K, Tang C, Volkmer AK, Naik TJ, Storm TA, Mosley AR, Edris B, Schmid SM, Sun CK, Chua MS, Murillo O, Rajendran P, Cha AC, Chin RK, Kim D, Adorno M, Raveh T, Tseng D, Jaiswal S, Enger PØ, Steinberg GK, Li G, So SK, Majeti R, Harsh GR, van de Rijn M, Teng NN, Sunwoo JB, Alizadeh AA, Clarke MF, Weissman IL. Willingham SB, et al. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6662-7. doi: 10.1073/pnas.1121623109. Epub 2012 Mar 26. Proc Natl Acad Sci U S A. 2012. PMID: 22451913 Free PMC article.
IKAROS levels are associated with antigen escape in CD19- and CD22-targeted therapies for B-cell malignancies.
Domizi P, Sarno J, Jager A, Merchant M, Pacheco KZB, Yamada-Hunter SA, Rotiroti MC, Liu Y, Baskar R, Reynolds WD, Sworder BJ, Sahaf B, Bendall SC, Mullighan CG, Alizadeh AA, Leahy AB, Myers RM, Yates B, Wang HW, Shah NN, Majzner RG, Mackall CL, Grupp SA, Barrett DM, Sotillo E, Davis KL. Domizi P, et al. Nat Commun. 2025 Apr 23;16(1):3800. doi: 10.1038/s41467-025-58868-2. Nat Commun. 2025. PMID: 40268897 Free PMC article.
Trait anxiety is related to Nx4's efficacy on stress-induced changes in amygdala-centered resting state functional connectivity: a placebo-controlled cross-over trial in mildly to moderately stressed healthy volunteers.
Nanni-Zepeda M, Alizadeh S, Chand T, Kasties V, Fan Y, van der Meer J, Herrmann L, Vester JC, Schulz M, Naschold B, Walter M. Nanni-Zepeda M, et al. BMC Neurosci. 2022 Nov 24;23(1):68. doi: 10.1186/s12868-022-00754-4. BMC Neurosci. 2022. PMID: 36434512 Free PMC article. Clinical Trial.
Abrupt shift of El Niño periodicity under CO2 mitigation.
Iwakiri T, Kug JS, Jin FF, Zhao S, An SI, Kim GI, Park D. Iwakiri T, et al. Proc Natl Acad Sci U S A. 2025 Jun 24;122(25):e2426048122. doi: 10.1073/pnas.2426048122. Epub 2025 Jun 16. Proc Natl Acad Sci U S A. 2025. PMID: 40523186 Free PMC article.
One of the most uncertain aspects of El Nino behavior is the change in periodicity in response to CO(2) forcing [O. Alizadeh, Earth-Sci. Rev. 235, 104246 (2022)]. In this study, we show that climate models consistently project an abrupt shortening of El Nino periodicity on …
One of the most uncertain aspects of El Nino behavior is the change in periodicity in response to CO(2) forcing [O. Alizadeh, Earth-S …
Feedback in the β-catenin destruction complex imparts bistability and cellular memory.
Cantoria MJ, Alizadeh E, Ravi J, Varghese RP, Bunnag N, Pond KW, Kettenbach AN, Ahmed Y, Paek AL, Tyson JJ, Doubrovinski K, Lee E, Thorne CA. Cantoria MJ, et al. Proc Natl Acad Sci U S A. 2023 Jan 10;120(2):e2208787120. doi: 10.1073/pnas.2208787120. Epub 2023 Jan 4. Proc Natl Acad Sci U S A. 2023. PMID: 36598937 Free PMC article.
Genetic variants linked to education predict longevity.
Marioni RE, Ritchie SJ, Joshi PK, Hagenaars SP, Okbay A, Fischer K, Adams MJ, Hill WD, Davies G; Social Science Genetic Association Consortium; Nagy R, Amador C, Läll K, Metspalu A, Liewald DC, Campbell A, Wilson JF, Hayward C, Esko T, Porteous DJ, Gale CR, Deary IJ. Marioni RE, et al. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):13366-13371. doi: 10.1073/pnas.1605334113. Epub 2016 Oct 31. Proc Natl Acad Sci U S A. 2016. PMID: 27799538 Free PMC article.
Diversity of intratumoral regulatory T cells in B-cell non-Hodgkin lymphoma.
Spasevska I, Sharma A, Steen CB, Josefsson SE, Blaker YN, Kolstad A, Rustad EH, Meyer S, Isaksen K, Chellappa S, Kushekhar K, Beiske K, Førsund MS, Spetalen S, Holte H, Østenstad B, Brodtkorb M, Kimby E, Olweus J, Taskén K, Newman AM, Lorenz S, Smeland EB, Alizadeh AA, Huse K, Myklebust JH. Spasevska I, et al. Blood Adv. 2023 Dec 12;7(23):7216-7230. doi: 10.1182/bloodadvances.2023010158. Blood Adv. 2023. PMID: 37695745 Free PMC article.
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