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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
1992 2
1993 3
1994 4
1995 3
1996 4
1997 2
1999 2
2000 1
2001 1
2002 1
2003 1
2004 3
2005 1
2006 1
2007 2
2010 1
2014 1
2016 3
2017 1
2018 1
2020 9
2021 5
2022 5
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57 results
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Page 1
IL-15 superagonist N-803 improves IFNγ production and killing of leukemia and ovarian cancer cells by CD34+ progenitor-derived NK cells.
Van der Meer JMR, Maas RJA, Guldevall K, Klarenaar K, de Jonge PKJD, Evert JSH, van der Waart AB, Cany J, Safrit JT, Lee JH, Wagena E, Friedl P, Önfelt B, Massuger LF, Schaap NPM, Jansen JH, Hobo W, Dolstra H. Van der Meer JMR, et al. Among authors: safrit jt. Cancer Immunol Immunother. 2021 May;70(5):1305-1321. doi: 10.1007/s00262-020-02749-8. Epub 2020 Nov 3. Cancer Immunol Immunother. 2021. PMID: 33140189 Free PMC article.
Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells.
McBrien JB, Mavigner M, Franchitti L, Smith SA, White E, Tharp GK, Walum H, Busman-Sahay K, Aguilera-Sandoval CR, Thayer WO, Spagnuolo RA, Kovarova M, Wahl A, Cervasi B, Margolis DM, Vanderford TH, Carnathan DG, Paiardini M, Lifson JD, Lee JH, Safrit JT, Bosinger SE, Estes JD, Derdeyn CA, Garcia JV, Kulpa DA, Chahroudi A, Silvestri G. McBrien JB, et al. Among authors: safrit jt. Nature. 2020 Feb;578(7793):154-159. doi: 10.1038/s41586-020-1946-0. Epub 2020 Jan 22. Nature. 2020. PMID: 31969705 Free PMC article.
Combinatorial immunotherapy of N-803 (IL-15 superagonist) and dinutuximab with ex vivo expanded natural killer cells significantly enhances in vitro cytotoxicity against GD2+ pediatric solid tumors and in vivo survival of xenografted immunodeficient NSG mice.
Chu Y, Nayyar G, Jiang S, Rosenblum JM, Soon-Shiong P, Safrit JT, Lee DA, Cairo MS. Chu Y, et al. Among authors: safrit jt. J Immunother Cancer. 2021 Jul;9(7):e002267. doi: 10.1136/jitc-2020-002267. J Immunother Cancer. 2021. PMID: 34244307 Free PMC article.
Safety and virologic impact of the IL-15 superagonist N-803 in people living with HIV: a phase 1 trial.
Miller JS, Davis ZB, Helgeson E, Reilly C, Thorkelson A, Anderson J, Lima NS, Jorstad S, Hart GT, Lee JH, Safrit JT, Wong H, Cooley S, Gharu L, Chung H, Soon-Shiong P, Dobrowolski C, Fletcher CV, Karn J, Douek DC, Schacker TW. Miller JS, et al. Among authors: safrit jt. Nat Med. 2022 Feb;28(2):392-400. doi: 10.1038/s41591-021-01651-9. Epub 2022 Jan 31. Nat Med. 2022. PMID: 35102335 Clinical Trial.
Dual-Antigen COVID-19 Vaccine Subcutaneous Prime Delivery With Oral Boosts Protects NHP Against SARS-CoV-2 Challenge.
Gabitzsch E, Safrit JT, Verma M, Rice A, Sieling P, Zakin L, Shin A, Morimoto B, Adisetiyo H, Wong R, Bezawada A, Dinkins K, Balint J, Peykov V, Garban H, Liu P, Bacon A, Bone P, Drew J, Sanford DC, Spilman P, Sender L, Rabizadeh S, Niazi K, Soon-Shiong P. Gabitzsch E, et al. Among authors: safrit jt. Front Immunol. 2021 Sep 16;12:729837. doi: 10.3389/fimmu.2021.729837. eCollection 2021. Front Immunol. 2021. PMID: 34603305 Free PMC article.
Immunoprophylaxis to prevent mother-to-child transmission of HIV-1.
Safrit JT, Ruprecht R, Ferrantelli F, Xu W, Kitabwalla M, Van Rompay K, Marthas M, Haigwood N, Mascola JR, Luzuriaga K, Jones SA, Mathieson BJ, Newell ML; Ghent IAS Working Group on HIV in Women Children. Safrit JT, et al. J Acquir Immune Defic Syndr. 2004 Feb 1;35(2):169-77. doi: 10.1097/00126334-200402010-00012. J Acquir Immune Defic Syndr. 2004. PMID: 14722451 Review.
57 results