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ARS2 instructs early transcription termination-coupled RNA decay by recruiting ZC3H4 to nascent transcripts.
Rouvière JO, Salerno-Kochan A, Lykke-Andersen S, Garland W, Dou Y, Rathore O, Molska EŠ, Wu G, Schmid M, Bugai A, Jakobsen L, Žumer K, Cramer P, Andersen JS, Conti E, Jensen TH. Rouvière JO, et al. Among authors: salerno kochan a. Mol Cell. 2023 Jul 6;83(13):2240-2257.e6. doi: 10.1016/j.molcel.2023.05.028. Epub 2023 Jun 16. Mol Cell. 2023. PMID: 37329882 Free article.
Elongator mutation in mice induces neurodegeneration and ataxia-like behavior.
Kojic M, Gaik M, Kiska B, Salerno-Kochan A, Hunt S, Tedoldi A, Mureev S, Jones A, Whittle B, Genovesi LA, Adolphe C, Brown DL, Stow JL, Alexandrov K, Sah P, Glatt S, Wainwright BJ. Kojic M, et al. Among authors: salerno kochan a. Nat Commun. 2018 Aug 10;9(1):3195. doi: 10.1038/s41467-018-05765-6. Nat Commun. 2018. PMID: 30097576 Free PMC article.
Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype.
Kojic M, Gawda T, Gaik M, Begg A, Salerno-Kochan A, Kurniawan ND, Jones A, Drożdżyk K, Kościelniak A, Chramiec-Głąbik A, Hediyeh-Zadeh S, Kasherman M, Shim WJ, Sinniah E, Genovesi LA, Abrahamsen RK, Fenger CD, Madsen CG, Cohen JS, Fatemi A, Stark Z, Lunke S, Lee J, Hansen JK, Boxill MF, Keren B, Marey I, Saenz MS, Brown K, Alexander SA, Mureev S, Batzilla A, Davis MJ, Piper M, Bodén M, Burne THJ, Palpant NJ, Møller RS, Glatt S, Wainwright BJ. Kojic M, et al. Among authors: salerno kochan a. Nat Commun. 2021 May 11;12(1):2678. doi: 10.1038/s41467-021-22888-5. Nat Commun. 2021. PMID: 33976153 Free PMC article.