In today's diagnostic imaging the heart with Pet 18F - FDG finds its highest expression in' identify the extent, severity, and the possibility of recovery of dysfunctional myocardium. Aim of this study was to extract some parameters "unique" as the regional metabolic rate, the speed of fractional irreversible binding of the tracer to the receptor sites in order to obtain a quantization of a possible damage of the tissue under examination. We used a dedicated software, the PMOD, implemented with compartmental models and graphical analysis methods in order to obtain absolute and repeatable results. In our results these parameters can give a qualitative data integration and definition to which, as is known, do not allow the identification of objective criteria to identify a possible ischemic damage and, most important, a possible recovery of dysfunctional myocardium.