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Ancestral Sequence Reconstruction of a Cytochrome P450 Family Involved in Chemical Defense Reveals the Functional Evolution of a Promiscuous, Xenobiotic-Metabolizing Enzyme in Vertebrates.
Harris KL, Thomson RES, Gumulya Y, Foley G, Carrera-Pacheco SE, Syed P, Janosik T, Sandinge AS, Andersson S, Jurva U, Bodén M, Gillam EMJ. Harris KL, et al. Among authors: sandinge as. Mol Biol Evol. 2022 Jun 2;39(6):msac116. doi: 10.1093/molbev/msac116. Mol Biol Evol. 2022. PMID: 35639613 Free PMC article.
Structural and functional characterization of a specific antidote for ticagrelor.
Buchanan A, Newton P, Pehrsson S, Inghardt T, Antonsson T, Svensson P, Sjögren T, Öster L, Janefeldt A, Sandinge AS, Keyes F, Austin M, Spooner J, Gennemark P, Penney M, Howells G, Vaughan T, Nylander S. Buchanan A, et al. Among authors: sandinge as. Blood. 2015 May 28;125(22):3484-90. doi: 10.1182/blood-2015-01-622928. Epub 2015 Mar 18. Blood. 2015. PMID: 25788700 Free PMC article.
Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein.
Davies N, Hovdal D, Edmunds N, Nordberg P, Dahlén A, Dabkowska A, Arteta MY, Radulescu A, Kjellman T, Höijer A, Seeliger F, Holmedal E, Andihn E, Bergenhem N, Sandinge AS, Johansson C, Hultin L, Johansson M, Lindqvist J, Björsson L, Jing Y, Bartesaghi S, Lindfors L, Andersson S. Davies N, et al. Among authors: sandinge as. Mol Ther Nucleic Acids. 2021 Mar 13;24:369-384. doi: 10.1016/j.omtn.2021.03.008. eCollection 2021 Jun 4. Mol Ther Nucleic Acids. 2021. PMID: 33868782 Free PMC article.
Unraveling the pharmacokinetic interaction of ticagrelor and MEDI2452 (Ticagrelor antidote) by mathematical modeling.
Almquist J, Penney M, Pehrsson S, Sandinge AS, Janefeldt A, Maqbool S, Madalli S, Goodman J, Nylander S, Gennemark P. Almquist J, et al. Among authors: sandinge as. CPT Pharmacometrics Syst Pharmacol. 2016 Jun;5(6):313-23. doi: 10.1002/psp4.12089. Epub 2016 Jun 16. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 27310493 Free PMC article.
11 results