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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
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1999 1
2000 1
2002 1
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2008 1
2010 4
2011 6
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2017 4
2018 2
2024 0

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28 results

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Page 1
Novel glucokinase activators: a patent review (2008 - 2010).
Sarabu R, Berthel SJ, Kester RF, Tilley JW. Sarabu R, et al. Expert Opin Ther Pat. 2011 Jan;21(1):13-33. doi: 10.1517/13543776.2011.542413. Epub 2010 Dec 15. Expert Opin Ther Pat. 2011. PMID: 21155690 Review.
Mutational analysis of allosteric activation and inhibition of glucokinase.
Zelent B, Odili S, Buettger C, Zelent DK, Chen P, Fenner D, Bass J, Stanley C, Laberge M, Vanderkooi JM, Sarabu R, Grimsby J, Matschinsky FM. Zelent B, et al. Among authors: sarabu r. Biochem J. 2011 Dec 1;440(2):203-15. doi: 10.1042/BJ20110440. Biochem J. 2011. PMID: 21831042 Free PMC article.
Discovery of piragliatin--first glucokinase activator studied in type 2 diabetic patients.
Sarabu R, Bizzarro FT, Corbett WL, Dvorozniak MT, Geng W, Grippo JF, Haynes NE, Hutchings S, Garofalo L, Guertin KR, Hilliard DW, Kabat M, Kester RF, Ka W, Liang Z, Mahaney PE, Marcus L, Matschinsky FM, Moore D, Racha J, Radinov R, Ren Y, Qi L, Pignatello M, Spence CL, Steele T, Tengi J, Grimsby J. Sarabu R, et al. J Med Chem. 2012 Aug 23;55(16):7021-36. doi: 10.1021/jm3008689. Epub 2012 Aug 1. J Med Chem. 2012. PMID: 22809456
2,3-Disubstituted acrylamides as potent glucokinase activators.
Sidduri A, Grimsby JS, Corbett WL, Sarabu R, Grippo JF, Lou J, Kester RF, Dvorozniak M, Marcus L, Spence C, Racha JK, Moore DJ. Sidduri A, et al. Among authors: sarabu r. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5673-6. doi: 10.1016/j.bmcl.2010.08.029. Epub 2010 Aug 11. Bioorg Med Chem Lett. 2010. PMID: 20805029
Discovery, structure-activity relationships, pharmacokinetics, and efficacy of glucokinase activator (2R)-3-cyclopentyl-2-(4-methanesulfonylphenyl)-N-thiazol-2-yl-propionamide (RO0281675).
Haynes NE, Corbett WL, Bizzarro FT, Guertin KR, Hilliard DW, Holland GW, Kester RF, Mahaney PE, Qi L, Spence CL, Tengi J, Dvorozniak MT, Railkar A, Matschinsky FM, Grippo JF, Grimsby J, Sarabu R. Haynes NE, et al. Among authors: sarabu r. J Med Chem. 2010 May 13;53(9):3618-25. doi: 10.1021/jm100039a. J Med Chem. 2010. PMID: 20405948
Allosteric activators of glucokinase: potential role in diabetes therapy.
Grimsby J, Sarabu R, Corbett WL, Haynes NE, Bizzarro FT, Coffey JW, Guertin KR, Hilliard DW, Kester RF, Mahaney PE, Marcus L, Qi L, Spence CL, Tengi J, Magnuson MA, Chu CA, Dvorozniak MT, Matschinsky FM, Grippo JF. Grimsby J, et al. Among authors: sarabu r. Science. 2003 Jul 18;301(5631):370-3. doi: 10.1126/science.1084073. Science. 2003. PMID: 12869762
28 results