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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1996 2
1998 1
2000 2
2001 1
2002 2
2003 2
2004 3
2005 5
2006 5
2007 4
2008 4
2009 6
2010 8
2011 5
2012 5
2013 4
2014 6
2015 1
2016 2
2017 8
2018 10
2019 10
2020 11
2021 17
2022 7
2023 9
2024 5

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132 results

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Page 1
Design of protein-binding proteins from the target structure alone.
Cao L, Coventry B, Goreshnik I, Huang B, Sheffler W, Park JS, Jude KM, Marković I, Kadam RU, Verschueren KHG, Verstraete K, Walsh STR, Bennett N, Phal A, Yang A, Kozodoy L, DeWitt M, Picton L, Miller L, Strauch EM, DeBouver ND, Pires A, Bera AK, Halabiya S, Hammerson B, Yang W, Bernard S, Stewart L, Wilson IA, Ruohola-Baker H, Schlessinger J, Lee S, Savvides SN, Garcia KC, Baker D. Cao L, et al. Among authors: savvides sn. Nature. 2022 May;605(7910):551-560. doi: 10.1038/s41586-022-04654-9. Epub 2022 Mar 24. Nature. 2022. PMID: 35332283 Free PMC article.
Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms.
Durham BH, Lopez Rodrigo E, Picarsic J, Abramson D, Rotemberg V, De Munck S, Pannecoucke E, Lu SX, Pastore A, Yoshimi A, Mandelker D, Ceyhan-Birsoy O, Ulaner GA, Walsh M, Yabe M, Petrova-Drus K, Arcila ME, Ladanyi M, Solit DB, Berger MF, Hyman DM, Lacouture ME, Erickson C, Saganty R, Ki M, Dunkel IJ, Santa-María López V, Mora J, Haroche J, Emile JF, Decaux O, Geissmann F, Savvides SN, Drilon A, Diamond EL, Abdel-Wahab O. Durham BH, et al. Among authors: savvides sn. Nat Med. 2019 Dec;25(12):1839-1842. doi: 10.1038/s41591-019-0653-6. Epub 2019 Nov 25. Nat Med. 2019. PMID: 31768065 Free PMC article.
Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma.
Verstraete K, Peelman F, Braun H, Lopez J, Van Rompaey D, Dansercoer A, Vandenberghe I, Pauwels K, Tavernier J, Lambrecht BN, Hammad H, De Winter H, Beyaert R, Lippens G, Savvides SN. Verstraete K, et al. Among authors: savvides sn. Nat Commun. 2017 Apr 3;8:14937. doi: 10.1038/ncomms14937. Nat Commun. 2017. PMID: 28368013 Free PMC article.
Ym1 protein crystals promote type 2 immunity.
Heyndrickx I, Deswarte K, Verstraete K, Verschueren KHG, Smole U, Aegerter H, Dansercoer A, Hammad H, Savvides SN, Lambrecht BN. Heyndrickx I, et al. Among authors: savvides sn. Elife. 2024 Jan 9;12:RP90676. doi: 10.7554/eLife.90676. Elife. 2024. PMID: 38194250 Free PMC article.
Rare Antagonistic Leptin Variants and Severe, Early-Onset Obesity.
Funcke JB, Moepps B, Roos J, von Schnurbein J, Verstraete K, Fröhlich-Reiterer E, Kohlsdorf K, Nunziata A, Brandt S, Tsirigotaki A, Dansercoer A, Suppan E, Haris B, Debatin KM, Savvides SN, Farooqi IS, Hussain K, Gierschik P, Fischer-Posovszky P, Wabitsch M. Funcke JB, et al. Among authors: savvides sn. N Engl J Med. 2023 Jun 15;388(24):2253-2261. doi: 10.1056/NEJMoa2204041. N Engl J Med. 2023. PMID: 37314706
Improving de novo protein binder design with deep learning.
Bennett NR, Coventry B, Goreshnik I, Huang B, Allen A, Vafeados D, Peng YP, Dauparas J, Baek M, Stewart L, DiMaio F, De Munck S, Savvides SN, Baker D. Bennett NR, et al. Among authors: savvides sn. Nat Commun. 2023 May 6;14(1):2625. doi: 10.1038/s41467-023-38328-5. Nat Commun. 2023. PMID: 37149653 Free PMC article.
Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Persson EK, Verstraete K, Heyndrickx I, Gevaert E, Aegerter H, Percier JM, Deswarte K, Verschueren KHG, Dansercoer A, Gras D, Chanez P, Bachert C, Gonçalves A, Van Gorp H, De Haard H, Blanchetot C, Saunders M, Hammad H, Savvides SN, Lambrecht BN. Persson EK, et al. Among authors: savvides sn. Science. 2019 May 24;364(6442):eaaw4295. doi: 10.1126/science.aaw4295. Science. 2019. PMID: 31123109
Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice.
Van Damme KFA, Hertens P, Martens A, Gilis E, Priem D, Bruggeman I, Fossoul A, Declercq J, Aegerter H, Wullaert A, Hochepied T, Hoste E, Vande Walle L, Lamkanfi M, Savvides SN, Elewaut D, Lambrecht BN, van Loo G. Van Damme KFA, et al. Among authors: savvides sn. Sci Rep. 2023 Oct 21;13(1):17992. doi: 10.1038/s41598-023-45324-8. Sci Rep. 2023. PMID: 37865713 Free PMC article.
Attenuated CSF-1R signalling drives cerebrovascular pathology.
Delaney C, Farrell M, Doherty CP, Brennan K, O'Keeffe E, Greene C, Byrne K, Kelly E, Birmingham N, Hickey P, Cronin S, Savvides SN, Doyle SL, Campbell M. Delaney C, et al. Among authors: savvides sn. EMBO Mol Med. 2021 Feb 5;13(2):e12889. doi: 10.15252/emmm.202012889. Epub 2020 Dec 22. EMBO Mol Med. 2021. PMID: 33350588 Free PMC article.
132 results