SBNO2 is a critical mediator of STAT3-driven hematological malignancies.
Brandstoetter T, Schmoellerl J, Grausenburger R, Kollmann S, Doma E, Huuhtanen J, Klampfl T, Eder T, Grebien F, Hoermann G, Zuber J, Mustjoki S, Maurer B, Sexl V.
Brandstoetter T, et al.
Blood. 2023 Apr 13;141(15):1831-1845. doi: 10.1182/blood.2022018494.
Blood. 2023.
PMID: 36630607
Free PMC article.
Among these, strawberry notch homolog 2 (SBNO2) represents an essential transcriptional target, which was identified by a comparative genome-wide CRISPR/Cas9-based loss-of-function screen. ...In patients with NPM-ALK+ T-ALCL, high SBNO2 expression correlates with sh …
Among these, strawberry notch homolog 2 (SBNO2) represents an essential transcriptional target, which was identified by a comparative …