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Year Number of Results
1997 1
1998 1
1999 1
2010 1
2012 1
2013 1
2015 1
2016 1
2017 1
2018 1
2019 1
2022 0
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The Novel Phosphodiesterase 9A Inhibitor BI 409306 Increases Cyclic Guanosine Monophosphate Levels in the Brain, Promotes Synaptic Plasticity, and Enhances Memory Function in Rodents.
Rosenbrock H, Giovannini R, Schänzle G, Koros E, Runge F, Fuchs H, Marti A, Reymann KG, Schröder UH, Fedele E, Dorner-Ciossek C. Rosenbrock H, et al. Among authors: schanzle g. J Pharmacol Exp Ther. 2019 Dec;371(3):633-641. doi: 10.1124/jpet.119.260059. Epub 2019 Oct 2. J Pharmacol Exp Ther. 2019. PMID: 31578258
An orally bioavailable positive allosteric modulator of the mGlu4 receptor with efficacy in an animal model of motor dysfunction.
East SP, Bamford S, Dietz MG, Eickmeier C, Flegg A, Ferger B, Gemkow MJ, Heilker R, Hengerer B, Kotey A, Loke P, Schänzle G, Schubert HD, Scott J, Whittaker M, Williams M, Zawadzki P, Gerlach K. East SP, et al. Among authors: schanzle g. Bioorg Med Chem Lett. 2010 Aug 15;20(16):4901-5. doi: 10.1016/j.bmcl.2010.06.078. Epub 2010 Jun 25. Bioorg Med Chem Lett. 2010. PMID: 20638279