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Page 1
Targeting senescent cells with NKG2D-CAR T cells.
Deng Y, Kumar A, Xie K, Schaaf K, Scifo E, Morsy S, Li T, Ehninger A, Bano D, Ehninger D. Deng Y, et al. Among authors: schaaf k. Cell Death Discov. 2024 May 4;10(1):217. doi: 10.1038/s41420-024-01976-7. Cell Death Discov. 2024. PMID: 38704364 Free PMC article.
microRNA-1 Regulates Metabolic Flexibility in Skeletal Muscle via Pyruvate Metabolism.
Ismaeel A, Peck BD, Montgomery MM, Burke BI, Goh J, Kang G, Franco AB, Xia Q, Goljanek-Whysall K, McDonagh B, McLendon JM, Koopmans PJ, Jacko D, Schaaf K, Bloch W, Gehlert S, Wen Y, Murach KA, Peterson CA, Boudreau RL, Fisher-Wellman KH, McCarthy JJ. Ismaeel A, et al. Among authors: schaaf k. bioRxiv [Preprint]. 2024 Aug 10:2024.08.09.607377. doi: 10.1101/2024.08.09.607377. bioRxiv. 2024. PMID: 39149347 Free PMC article. Preprint.
Force-induced dephosphorylation activates the cochaperone BAG3 to coordinate protein homeostasis and membrane traffic.
Ottensmeyer J, Esch A, Baeta H, Sieger S, Gupta Y, Rathmann MF, Jeschke A, Jacko D, Schaaf K, Schiffer T, Rahimi B, Lövenich L, Sisto A, van der Ven PFM, Fürst DO, Haas A, Bloch W, Gehlert S, Hoffmann B, Timmerman V, Huesgen PF, Höhfeld J. Ottensmeyer J, et al. Among authors: schaaf k. Curr Biol. 2024 Sep 23;34(18):4170-4183.e9. doi: 10.1016/j.cub.2024.07.088. Epub 2024 Aug 23. Curr Biol. 2024. PMID: 39181128 Free article.
Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.
Xie K, Fuchs H, Scifo E, Liu D, Aziz A, Aguilar-Pimentel JA, Amarie OV, Becker L, da Silva-Buttkus P, Calzada-Wack J, Cho YL, Deng Y, Edwards AC, Garrett L, Georgopoulou C, Gerlini R, Hölter SM, Klein-Rodewald T, Kramer M, Leuchtenberger S, Lountzi D, Mayer-Kuckuk P, Nover LL, Oestereicher MA, Overkott C, Pearson BL, Rathkolb B, Rozman J, Russ J, Schaaf K, Spielmann N, Sanz-Moreno A, Stoeger C, Treise I, Bano D, Busch DH, Graw J, Klingenspor M, Klopstock T, Mock BA, Salomoni P, Schmidt-Weber C, Weiergräber M, Wolf E, Wurst W, Gailus-Durner V, Breteler MMB, Hrabě de Angelis M, Ehninger D. Xie K, et al. Among authors: schaaf k. Nat Commun. 2022 Nov 11;13(1):6830. doi: 10.1038/s41467-022-34515-y. Nat Commun. 2022. PMID: 36369285 Free PMC article.
Enhancer-associated H3K4 methylation safeguards in vitro germline competence.
Bleckwehl T, Crispatzu G, Schaaf K, Respuela P, Bartusel M, Benson L, Clark SJ, Dorighi KM, Barral A, Laugsch M, van IJcken WFJ, Manzanares M, Wysocka J, Reik W, Rada-Iglesias Á. Bleckwehl T, et al. Among authors: schaaf k. Nat Commun. 2021 Oct 1;12(1):5771. doi: 10.1038/s41467-021-26065-6. Nat Commun. 2021. PMID: 34599190 Free PMC article.
Cell-free hemoglobin triggers macrophage cytokine production via TLR4 and MyD88.
Schaaf KR, Landstreet SR, Pugazenthi S, Qian EY, Putz ND, Siderova T, Owen AM, Bohannon JK, Ware LB, Bastarache JA, Shaver CM. Schaaf KR, et al. Am J Physiol Lung Cell Mol Physiol. 2024 Jan 1;326(1):L29-L38. doi: 10.1152/ajplung.00123.2023. Epub 2023 Nov 22. Am J Physiol Lung Cell Mol Physiol. 2024. PMID: 37991487 Free PMC article.
Acute exercise boosts NAD+ metabolism of human peripheral blood mononuclear cells.
Walzik D, Joisten N, Schenk A, Trebing S, Schaaf K, Metcalfe AJ, Spiliopoulou P, Hiefner J, McCann A, Watzl C, Ueland PM, Gehlert S, Worthmann A, Brenner C, Zimmer P. Walzik D, et al. Among authors: schaaf k. Brain Behav Immun. 2025 Jan;123:1011-1023. doi: 10.1016/j.bbi.2024.11.004. Epub 2024 Nov 3. Brain Behav Immun. 2025. PMID: 39500416 Free article. Clinical Trial.
52 results