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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 3
2000 2
2001 7
2002 2
2003 5
2004 3
2005 5
2006 5
2007 9
2008 25
2009 13
2010 12
2011 22
2012 14
2013 18
2014 12
2015 15
2016 12
2017 9
2018 14
2019 13
2020 14
2021 11
2022 14
2023 2
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Search Results

237 results
Results by year
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Page 1
Biological and clinical consequences of NPM1 mutations in AML.
Heath EM, Chan SM, Minden MD, Murphy T, Shlush LI, Schimmer AD. Heath EM, et al. Among authors: schimmer ad. Leukemia. 2017 Apr;31(4):798-807. doi: 10.1038/leu.2017.30. Epub 2017 Jan 23. Leukemia. 2017. PMID: 28111462 Review.
Venetoclax enhances T cell-mediated antileukemic activity by increasing ROS production.
Lee JB, Khan DH, Hurren R, Xu M, Na Y, Kang H, Mirali S, Wang X, Gronda M, Jitkova Y, MacLean N, Arruda A, Alaniz Z, Konopleva MY, Andreeff M, Minden MD, Zhang L, Schimmer AD. Lee JB, et al. Among authors: schimmer ad. Blood. 2021 Jul 22;138(3):234-245. doi: 10.1182/blood.2020009081. Blood. 2021. PMID: 34292323 Free PMC article.
A 17-gene stemness score for rapid determination of risk in acute leukaemia.
Ng SW, Mitchell A, Kennedy JA, Chen WC, McLeod J, Ibrahimova N, Arruda A, Popescu A, Gupta V, Schimmer AD, Schuh AC, Yee KW, Bullinger L, Herold T, Görlich D, Büchner T, Hiddemann W, Berdel WE, Wörmann B, Cheok M, Preudhomme C, Dombret H, Metzeler K, Buske C, Löwenberg B, Valk PJ, Zandstra PW, Minden MD, Dick JE, Wang JC. Ng SW, et al. Among authors: schimmer ad. Nature. 2016 Dec 15;540(7633):433-437. doi: 10.1038/nature20598. Epub 2016 Dec 7. Nature. 2016. PMID: 27926740
Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality.
Ishizawa J, Zarabi SF, Davis RE, Halgas O, Nii T, Jitkova Y, Zhao R, St-Germain J, Heese LE, Egan G, Ruvolo VR, Barghout SH, Nishida Y, Hurren R, Ma W, Gronda M, Link T, Wong K, Mabanglo M, Kojima K, Borthakur G, MacLean N, Ma MCJ, Leber AB, Minden MD, Houry W, Kantarjian H, Stogniew M, Raught B, Pai EF, Schimmer AD, Andreeff M. Ishizawa J, et al. Among authors: schimmer ad. Cancer Cell. 2019 May 13;35(5):721-737.e9. doi: 10.1016/j.ccell.2019.03.014. Epub 2019 May 2. Cancer Cell. 2019. PMID: 31056398 Free PMC article.
Very long chain fatty acid metabolism is required in acute myeloid leukemia.
Tcheng M, Roma A, Ahmed N, Smith RW, Jayanth P, Minden MD, Schimmer AD, Hess DA, Hope K, Rea KA, Akhtar TA, Bohrnsen E, D'Alessandro A, Mohsen AW, Vockley J, Spagnuolo PA. Tcheng M, et al. Among authors: schimmer ad. Blood. 2021 Jun 24;137(25):3518-3532. doi: 10.1182/blood.2020008551. Blood. 2021. PMID: 33720355 Free PMC article.
E1 Enzymes as Therapeutic Targets in Cancer.
Barghout SH, Schimmer AD. Barghout SH, et al. Among authors: schimmer ad. Pharmacol Rev. 2021 Jan;73(1):1-58. doi: 10.1124/pharmrev.120.000053. Pharmacol Rev. 2021. PMID: 33177128 Review.
The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness.
Thomas GE, Egan G, García-Prat L, Botham A, Voisin V, Patel PS, Hoff FW, Chin J, Nachmias B, Kaufmann KB, Khan DH, Hurren R, Wang X, Gronda M, MacLean N, O'Brien C, Singh RP, Jones CL, Harding SM, Raught B, Arruda A, Minden MD, Bader GD, Hakem R, Kornblau S, Dick JE, Schimmer AD. Thomas GE, et al. Among authors: schimmer ad. Nat Cell Biol. 2022 Jun;24(6):872-884. doi: 10.1038/s41556-022-00925-9. Epub 2022 Jun 6. Nat Cell Biol. 2022. PMID: 35668135 Free PMC article.
Mammary epithelial cells have lineage-rooted metabolic identities.
Mahendralingam MJ, Kim H, McCloskey CW, Aliar K, Casey AE, Tharmapalan P, Pellacani D, Ignatchenko V, Garcia-Valero M, Palomero L, Sinha A, Cruickshank J, Shetty R, Vellanki RN, Koritzinsky M, Stambolic V, Alam M, Schimmer AD, Berman HK, Eaves CJ, Pujana MA, Kislinger T, Khokha R. Mahendralingam MJ, et al. Among authors: schimmer ad. Nat Metab. 2021 May;3(5):665-681. doi: 10.1038/s42255-021-00388-6. Epub 2021 May 20. Nat Metab. 2021. PMID: 34031589
Targeting the Ubiquitin-Proteasome System Using the UBA1 Inhibitor TAK-243 is a Potential Therapeutic Strategy for Small-Cell Lung Cancer.
Majeed S, Aparnathi MK, Nixon KCJ, Venkatasubramanian V, Rahman F, Song L, Weiss J, Barayan R, Sugumar V, Barghout SH, Pearson JD, Bremner R, Schimmer AD, Tsao MS, Liu G, Lok BH. Majeed S, et al. Among authors: schimmer ad. Clin Cancer Res. 2022 May 2;28(9):1966-1978. doi: 10.1158/1078-0432.CCR-21-0344. Clin Cancer Res. 2022. PMID: 35165102 Free PMC article.
237 results