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Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection.
Ma L, Sahu SK, Cano M, Kuppuswamy V, Bajwa J, McPhatter J, Pine A, Meizlish M, Goshua G, Chang CH, Zhang H, Price C, Bahel P, Rinder H, Lei T, Day A, Reynolds D, Wu X, Schriefer R, Rauseo AM, Goss CW, O'Halloran JA, Presti RM, Kim AH, Gelman AE, Cruz CD, Lee AI, Mudd P, Chun HJ, Atkinson JP, Kulkarni HS. Ma L, et al. Among authors: schriefer r. bioRxiv. 2021 Feb 23:2021.02.22.432177. doi: 10.1101/2021.02.22.432177. Preprint. bioRxiv. 2021. PMID: 33655244 Free PMC article.
Glucocorticoids and B Cell Depleting Agents Substantially Impair Immunogenicity of mRNA Vaccines to SARS-CoV-2.
Deepak P, Kim W, Paley MA, Yang M, Carvidi AB, El-Qunni AA, Haile A, Huang K, Kinnett B, Liebeskind MJ, Liu Z, McMorrow LE, Paez D, Perantie DC, Schriefer RE, Sides SE, Thapa M, Gergely M, Abushamma S, Klebert M, Mitchell L, Nix D, Graf J, Taylor KE, Chahin S, Ciorba MA, Katz P, Matloubian M, O'Halloran JA, Presti RM, Wu GF, Whelan SPJ, Buchser WJ, Gensler LS, Nakamura MC, Ellebedy AH, Kim AHJ. Deepak P, et al. Among authors: schriefer re. medRxiv. 2021 Apr 9:2021.04.05.21254656. doi: 10.1101/2021.04.05.21254656. Preprint. medRxiv. 2021. PMID: 33851176 Free PMC article.