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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 1
1983 1
1984 1
1985 3
1986 1
1987 2
1988 2
1989 7
1990 5
1991 4
1992 3
1993 6
1994 3
1995 1
1996 3
1998 1
2002 6
2004 1
2005 2
2006 3
2007 6
2008 2
2009 4
2010 2
2011 3
2012 2
2013 5
2014 3
2015 1
2017 1
2021 3
2024 1

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88 results

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Page 1
New advances in treating thrombotic diseases.
Schumacher WA, Wang X, Wong PC. Schumacher WA, et al. Drug Discov Today. 2014 Sep;19(9):1433-4. doi: 10.1016/j.drudis.2014.06.015. Epub 2014 Jun 21. Drug Discov Today. 2014. PMID: 24959954 No abstract available.
Inhibition of factor XIa as a new approach to anticoagulation.
Schumacher WA, Luettgen JM, Quan ML, Seiffert DA. Schumacher WA, et al. Arterioscler Thromb Vasc Biol. 2010 Mar;30(3):388-92. doi: 10.1161/ATVBAHA.109.197178. Epub 2010 Feb 5. Arterioscler Thromb Vasc Biol. 2010. PMID: 20139363 Review.
Identification of 6-Hydroxypyrimidin-4(1H)-one-3-carboxamides as Potent and Orally Active APJ Receptor Agonists.
Pi Z, Johnson JA, Meng W, Phillips M, Schumacher WA, Bostwick JS, Gargalovic PS, Onorato JM, Generaux CN, Wang T, He Y, Gordon DA, Wexler RR, Finlay HJ. Pi Z, et al. Among authors: schumacher wa. ACS Med Chem Lett. 2021 Oct 22;12(11):1766-1772. doi: 10.1021/acsmedchemlett.1c00385. eCollection 2021 Nov 11. ACS Med Chem Lett. 2021. PMID: 34795866 Free PMC article.
Discovery of a Hydroxypyridinone APJ Receptor Agonist as a Clinical Candidate.
Johnson JA, Kim SH, Jiang J, Phillips M, Schumacher WA, Bostwick JS, Gargalovic PS, Onorato JM, Luk CE, Generaux C, He Y, Chen XQ, Xu C, Galella MA, Wang T, Gordon DA, Wexler RR, Finlay HJ. Johnson JA, et al. Among authors: schumacher wa. J Med Chem. 2021 Mar 25;64(6):3086-3099. doi: 10.1021/acs.jmedchem.0c01878. Epub 2021 Mar 9. J Med Chem. 2021. PMID: 33689340
Blockade of protease-activated receptor-4 (PAR4) provides robust antithrombotic activity with low bleeding.
Wong PC, Seiffert D, Bird JE, Watson CA, Bostwick JS, Giancarli M, Allegretto N, Hua J, Harden D, Guay J, Callejo M, Miller MM, Lawrence RM, Banville J, Guy J, Maxwell BD, Priestley ES, Marinier A, Wexler RR, Bouvier M, Gordon DA, Schumacher WA, Yang J. Wong PC, et al. Among authors: schumacher wa. Sci Transl Med. 2017 Jan 4;9(371):eaaf5294. doi: 10.1126/scitranslmed.aaf5294. Sci Transl Med. 2017. PMID: 28053157
Platelet depletion in experimental myocardial infarction.
Jolly SR, Schumacher WA, Kunkel SL, Abrams GD, Liddicoat J, Lucchesi BR. Jolly SR, et al. Among authors: schumacher wa. Basic Res Cardiol. 1985 May-Jun;80(3):269-79. doi: 10.1007/BF01907903. Basic Res Cardiol. 1985. PMID: 4026785 Free article.
Discovery of diarylurea P2Y(1) antagonists with improved aqueous solubility.
Wang TC, Qiao JX, Clark CG, Jua J, Price LA, Wu Q, Chang M, Zheng J, Huang CS, Everlof G, Schumacher WA, Wong PC, Seiffert DA, Stewart AB, Bostwick JS, Crain EJ, Watson CA, Rehfuss R, Wexler RR, Lam PY. Wang TC, et al. Among authors: schumacher wa. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3239-43. doi: 10.1016/j.bmcl.2013.03.125. Epub 2013 Apr 6. Bioorg Med Chem Lett. 2013. PMID: 23602442
Discovery of Potent and Selective Quinoxaline-Based Protease-Activated Receptor 4 (PAR4) Antagonists for the Prevention of Arterial Thrombosis.
Zhang X, Jiang W, Richter JM, Bates JA, Reznik SK, Stachura S, Rampulla R, Doddalingappa D, Ulaganathan S, Hua J, Bostwick JS, Sum C, Posy S, Malmstrom S, Dickey J, Harden D, Lawrence RM, Guarino VR, Schumacher WA, Wong P, Yang J, Gordon DA, Wexler RR, Priestley ES. Zhang X, et al. Among authors: schumacher wa. J Med Chem. 2024 Feb 22. doi: 10.1021/acs.jmedchem.3c01986. Online ahead of print. J Med Chem. 2024. PMID: 38385264
Discovery of 2-(phenoxypyridine)-3-phenylureas as small molecule P2Y1 antagonists.
Chao H, Turdi H, Herpin TF, Roberge JY, Liu Y, Schnur DM, Poss MA, Rehfuss R, Hua J, Wu Q, Price LA, Abell LM, Schumacher WA, Bostwick JS, Steinbacher TE, Stewart AB, Ogletree ML, Huang CS, Chang M, Cacace AM, Arcuri MJ, Celani D, Wexler RR, Lawrence RM. Chao H, et al. Among authors: schumacher wa. J Med Chem. 2013 Feb 28;56(4):1704-14. doi: 10.1021/jm301708u. Epub 2013 Feb 18. J Med Chem. 2013. PMID: 23368907
88 results