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The infrapatellar fat pad produces interleukin-6-secreting T cells in response to a proteoglycan aggrecan peptide and provides dominant soluble mediators different from that present in synovial fluid.
Sae-Jung T, Leearamwat N, Chaiseema N, Sengprasert P, Ngarmukos S, Yuktananda P, Tanavalee A, Hirankarn N, Reantragoon R. Sae-Jung T, et al. Among authors: sengprasert p. Int J Rheum Dis. 2021 Jun;24(6):834-846. doi: 10.1111/1756-185X.14126. Epub 2021 May 18. Int J Rheum Dis. 2021. PMID: 34008313
Infrapatellar fat pad adipose tissue-derived macrophages display a predominant CD11c+CD206+ phenotype and express genotypes attributable to key features of OA pathogenesis.
Hengtrakool P, Leearamwat N, Sengprasert P, Wongphoom J, Chaichana T, Taweevisit M, Ngarmukos S, Tanavalee A, Palaga T, Reantragoon R. Hengtrakool P, et al. Among authors: sengprasert p. Front Immunol. 2024 Feb 1;15:1326953. doi: 10.3389/fimmu.2024.1326953. eCollection 2024. Front Immunol. 2024. PMID: 38361943 Free PMC article.
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