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Showing results for sierocki p[au]
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ERAP Inhibitors in Autoimmunity and Immuno-Oncology: Medicinal Chemistry Insights.
Fougiaxis V, He B, Khan T, Vatinel R, Koutroumpa NM, Afantitis A, Lesire L, Sierocki P, Deprez B, Deprez-Poulain R. Fougiaxis V, et al. Among authors: sierocki p. J Med Chem. 2024 Jul 25;67(14):11597-11621. doi: 10.1021/acs.jmedchem.4c00840. Epub 2024 Jul 16. J Med Chem. 2024. PMID: 39011823 Free PMC article. Review.
First fragment-based screening identifies new chemotypes inhibiting ERAP1-metalloprotease.
Fougiaxis V, Barcherini V, Petrovic MM, Sierocki P, Warenghem S, Leroux F, Bou Karroum N, Petit-Cancelier F, Rodeschini V, Roche D, Deprez B, Deprez-Poulain R. Fougiaxis V, et al. Among authors: sierocki p. Eur J Med Chem. 2024 Dec 15;280:116926. doi: 10.1016/j.ejmech.2024.116926. Epub 2024 Sep 30. Eur J Med Chem. 2024. PMID: 39369482 Free article.
Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target-Guided Synthesis.
Camberlein V, Fléau C, Sierocki P, Li L, Gealageas R, Bosc D, Guillaume V, Warenghem S, Leroux F, Rosell M, Cheng K, Medve L, Prigent M, Decanter M, Piveteau C, Biela A, Eveque M, Dumont J, Mpakali A, Giastas P, Herledan A, Couturier C, Haupenthal J, Lesire L, Hirsch AKH, Deprez B, Stratikos E, Bouvier M, Deprez-Poulain R. Camberlein V, et al. Among authors: sierocki p. Angew Chem Int Ed Engl. 2022 Sep 26;61(39):e202203560. doi: 10.1002/anie.202203560. Epub 2022 Aug 19. Angew Chem Int Ed Engl. 2022. PMID: 35904863 Free PMC article.