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2015 1
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2020 1
2021 0
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Disrupting the platelet internal membrane via PI3KC2α inhibition impairs thrombosis independently of canonical platelet activation.
Selvadurai MV, Moon MJ, Mountford SJ, Ma X, Zheng Z, Jennings IG, Setiabakti NM, Iman RP, Brazilek RJ, Z Abidin NA, Chicanne G, Severin S, Nicholls AJ, Wong CHY, Rinckel JY, Eckly A, Gachet C, Nesbitt WS, Thompson PE, Hamilton JR. Selvadurai MV, et al. Among authors: setiabakti nm. Sci Transl Med. 2020 Jul 22;12(553):eaar8430. doi: 10.1126/scitranslmed.aar8430. Sci Transl Med. 2020. PMID: 32718993
The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function.
Mountford JK, Petitjean C, Putra HW, McCafferty JA, Setiabakti NM, Lee H, Tønnesen LL, McFadyen JD, Schoenwaelder SM, Eckly A, Gachet C, Ellis S, Voss AK, Dickins RA, Hamilton JR, Jackson SP. Mountford JK, et al. Among authors: setiabakti nm. Nat Commun. 2015 Mar 17;6:6535. doi: 10.1038/ncomms7535. Nat Commun. 2015. PMID: 25779105 Free article.