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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 3
1987 5
1988 2
1990 1
1991 2
1992 2
1993 1
1994 6
1995 6
1996 2
1997 3
1998 3
1999 5
2000 5
2001 1
2002 5
2003 3
2004 12
2005 12
2006 9
2007 13
2008 13
2009 11
2010 17
2011 17
2012 19
2013 17
2014 18
2015 16
2016 29
2017 16
2018 32
2019 13
2020 19
2021 20
2022 7
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Article type
Publication date

Search Results

330 results
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Page 1
From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease.
Brown AJH, Bradley SJ, Marshall FH, Brown GA, Bennett KA, Brown J, Cansfield JE, Cross DM, de Graaf C, Hudson BD, Dwomoh L, Dias JM, Errey JC, Hurrell E, Liptrot J, Mattedi G, Molloy C, Nathan PJ, Okrasa K, Osborne G, Patel JC, Pickworth M, Robertson N, Shahabi S, Bundgaard C, Phillips K, Broad LM, Goonawardena AV, Morairty SR, Browning M, Perini F, Dawson GR, Deakin JFW, Smith RT, Sexton PM, Warneck J, Vinson M, Tasker T, Tehan BG, Teobald B, Christopoulos A, Langmead CJ, Jazayeri A, Cooke RM, Rucktooa P, Congreve MS, Weir M, Tobin AB. Brown AJH, et al. Among authors: sexton pm. Cell. 2021 Nov 24;184(24):5886-5901.e22. doi: 10.1016/j.cell.2021.11.001. Cell. 2021. PMID: 34822784 Clinical Trial.
Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia.
Draper-Joyce CJ, Bhola R, Wang J, Bhattarai A, Nguyen ATN, Cowie-Kent I, O'Sullivan K, Chia LY, Venugopal H, Valant C, Thal DM, Wootten D, Panel N, Carlsson J, Christie MJ, White PJ, Scammells P, May LT, Sexton PM, Danev R, Miao Y, Glukhova A, Imlach WL, Christopoulos A. Draper-Joyce CJ, et al. Among authors: sexton pm. Nature. 2021 Sep;597(7877):571-576. doi: 10.1038/s41586-021-03897-2. Epub 2021 Sep 8. Nature. 2021. PMID: 34497422 Free PMC article.
Evolving cryo-EM structural approaches for GPCR drug discovery.
Zhang X, Johnson RM, Drulyte I, Yu L, Kotecha A, Danev R, Wootten D, Sexton PM, Belousoff MJ. Zhang X, et al. Among authors: sexton pm. Structure. 2021 Sep 2;29(9):963-974.e6. doi: 10.1016/j.str.2021.04.008. Epub 2021 May 5. Structure. 2021. PMID: 33957078
Structure and dynamics of the CGRP receptor in apo and peptide-bound forms.
Josephs TM, Belousoff MJ, Liang YL, Piper SJ, Cao J, Garama DJ, Leach K, Gregory KJ, Christopoulos A, Hay DL, Danev R, Wootten D, Sexton PM. Josephs TM, et al. Among authors: sexton pm. Science. 2021 Apr 9;372(6538):eabf7258. doi: 10.1126/science.abf7258. Epub 2021 Feb 18. Science. 2021. PMID: 33602864
Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists.
Zhang X, Belousoff MJ, Zhao P, Kooistra AJ, Truong TT, Ang SY, Underwood CR, Egebjerg T, Šenel P, Stewart GD, Liang YL, Glukhova A, Venugopal H, Christopoulos A, Furness SGB, Miller LJ, Reedtz-Runge S, Langmead CJ, Gloriam DE, Danev R, Sexton PM, Wootten D. Zhang X, et al. Among authors: sexton pm. Mol Cell. 2020 Nov 5;80(3):485-500.e7. doi: 10.1016/j.molcel.2020.09.020. Epub 2020 Oct 6. Mol Cell. 2020. PMID: 33027691 Free article.
Calcitonin.
Findlay DM, Sexton PM. Findlay DM, et al. Among authors: sexton pm. Growth Factors. 2004 Dec;22(4):217-24. doi: 10.1080/08977190410001728033. Growth Factors. 2004. PMID: 15621724 Review. No abstract available.
Calcitonin.
Sexton PM, Findlay DM, Martin TJ. Sexton PM, et al. Curr Med Chem. 1999 Nov;6(11):1067-93. Curr Med Chem. 1999. PMID: 10519914 Review.
Light-activated chimeric GPCRs: limitations and opportunities.
Tichy AM, Gerrard EJ, Sexton PM, Janovjak H. Tichy AM, et al. Among authors: sexton pm. Curr Opin Struct Biol. 2019 Aug;57:196-203. doi: 10.1016/j.sbi.2019.05.006. Epub 2019 Jun 14. Curr Opin Struct Biol. 2019. PMID: 31207383 Review.
330 results