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Snakehead vesiculovirus hijacks SH3RF1 for replication via mediating K63-linked ubiquitination at K264 of the phosphoprotein.
Qin X, Jiang N, Zhu J, Zhang YA, Tu J. Qin X, et al. Int J Biol Macromol. 2024 Jan;255:128201. doi: 10.1016/j.ijbiomac.2023.128201. Epub 2023 Nov 17. Int J Biol Macromol. 2024. PMID: 37979762
RNAi screening of 26 cellular E3 ubiquitin ligases identified five pro-viral factors for SHVV replication, including macrophage erythroblast attacher (MAEA), TNF receptor-associated factor 7 (TRAF7), and SH3 domain-containing ring finger protein 1 (SH3RF1), which interacte …
RNAi screening of 26 cellular E3 ubiquitin ligases identified five pro-viral factors for SHVV replication, including macrophage erythroblast …
Assessing the role of SH3RF1 and SH3RF2 polymorphisms in susceptibility to tuberculosis: A case-control study in the Han Chinese population.
Chen H, Zhou J, Jiao L, Song J, Zhong H, Zhao Z, Meng Z, Lu X, Chen X, Zhang W, Ying B. Chen H, et al. Microb Pathog. 2021 Mar;152:104567. doi: 10.1016/j.micpath.2020.104567. Epub 2020 Oct 28. Microb Pathog. 2021. PMID: 33129950
BACKGROUND: Tuberculosis (TB) remains a major public health problem. SH3RF1 and SH3RF2 are candidate genes with multiple single-nucleotide polymorphisms (SNPs) that have the potential to participate in Mycobacterium infection via activation of the JNK signaling pathway. In …
BACKGROUND: Tuberculosis (TB) remains a major public health problem. SH3RF1 and SH3RF2 are candidate genes with multiple single-nucle …
Integrative transcriptomic analysis of the amyotrophic lateral sclerosis spinal cord implicates glial activation and suggests new risk genes.
Humphrey J, Venkatesh S, Hasan R, Herb JT, de Paiva Lopes K, Küçükali F, Byrska-Bishop M, Evani US, Narzisi G, Fagegaltier D; NYGC ALS Consortium; Sleegers K, Phatnani H, Knowles DA, Fratta P, Raj T. Humphrey J, et al. Nat Neurosci. 2023 Jan;26(1):150-162. doi: 10.1038/s41593-022-01205-3. Epub 2022 Dec 8. Nat Neurosci. 2023. PMID: 36482247
We mapped molecular quantitative trait loci and found several potential ALS risk loci that may act through gene expression or splicing in the spinal cord and assign putative cell types for FNBP1, ACSL5, SH3RF1 and NFASC. Finally, we outline how common genetic variants asso …
We mapped molecular quantitative trait loci and found several potential ALS risk loci that may act through gene expression or splicing in th …
Protein interaction screening identifies SH3RF1 as a new regulator of FAT1 protein levels.
de Bock CE, Hughes MR, Snyder K, Alley S, Sadeqzadeh E, Dun MD, McNagny KM, Molloy TJ, Hondermarck H, Thorne RF. de Bock CE, et al. FEBS Lett. 2017 Feb;591(4):667-678. doi: 10.1002/1873-3468.12569. Epub 2017 Feb 16. FEBS Lett. 2017. PMID: 28129444 Free article.
A yeast two-hybrid library screen carried out against the juxtamembrane region of the cytoplasmic tail of FAT1 identified the E3 ubiquitin-protein ligase SH3RF1 as the most frequently recovered protein-binding partner. Ablating SH3RF1 using siRNA increased cellular …
A yeast two-hybrid library screen carried out against the juxtamembrane region of the cytoplasmic tail of FAT1 identified the E3 ubiquitin-p …
Identification of common biomarkers in diabetic kidney disease and cognitive dysfunction using machine learning algorithms.
Peng J, Yang S, Zhou C, Qin C, Fang K, Tan Y, Da J, Zhang J, Zha Y. Peng J, et al. Sci Rep. 2024 Sep 27;14(1):22057. doi: 10.1038/s41598-024-72327-w. Sci Rep. 2024. PMID: 39333211 Free PMC article.
The results demonstrated the up-regulation of SH3RF1 in the cortex, hippocampus and kidney of mice, which was further confirmed by immunofluorescence and Western blot validation. Notably, SH3RF1 is a scaffold protein involved in cell survival in the JNK signaling pa …
The results demonstrated the up-regulation of SH3RF1 in the cortex, hippocampus and kidney of mice, which was further confirmed by im …
Molecular characterization of the apoptosis-related SH3RF1 and SH3RF2 genes and their association with exercise performance in Arabian horses.
Ropka-Molik K, Stefaniuk-Szmukier M, Piórkowska K, Szmatoła T, Bugno-Poniewierska M. Ropka-Molik K, et al. BMC Vet Res. 2018 Aug 14;14(1):237. doi: 10.1186/s12917-018-1567-0. BMC Vet Res. 2018. PMID: 30107803 Free PMC article.
The highest SH3RF2 expression level was detected in the muscles of untrained horses, whereas the lowest expression was identified at the end of the racing season in horses that were fully adapted to the exercise. A non-significant decrease in SH3RF1 gene expression followi …
The highest SH3RF2 expression level was detected in the muscles of untrained horses, whereas the lowest expression was identified at the end …
Integration of Automatic Text Mining and Genomic and Proteomic Analysis to Unravel Prostate Cancer Biomarkers.
Lima T, Ferreira R, Freitas M, Henrique R, Vitorino R, Fardilha M. Lima T, et al. J Proteome Res. 2022 Feb 4;21(2):447-458. doi: 10.1021/acs.jproteome.1c00763. Epub 2022 Jan 4. J Proteome Res. 2022. PMID: 35114790
This study suggests AXIN2, GSTM2, KLK3, LGALS3, MSMB, PRTFDC1, and SH3RF1 as important entities in PCa context. KLK, LGALS3, and MSMB proteins are common to a previous bioinformatic analysis, and a concordance was found between the levels of gene and protein expression. .. …
This study suggests AXIN2, GSTM2, KLK3, LGALS3, MSMB, PRTFDC1, and SH3RF1 as important entities in PCa context. KLK, LGALS3, and MSMB …
Imputation-based association analyses identify new lung cancer susceptibility variants in CDK6 and SH3RF1 and their interactions with smoking in Chinese populations.
Deng Q, Guo H, Dai J, Yang L, Wu C, Wang Q, Hu Z, Yang M, Liu L, Yu D, Hu D, Hong X, Qiu F, Yang H, Wang T, Tan W, Chu M, Feng J, Teng K, Gong J, Sun C, Hu X, Zhang K, Lu J, Lin D, Shen H, Wu T. Deng Q, et al. Carcinogenesis. 2013 Sep;34(9):2010-6. doi: 10.1093/carcin/bgt145. Epub 2013 May 3. Carcinogenesis. 2013. PMID: 23644744

We found a genome-wide significant (P < 5.0 10(-8)) association for rs2282987 in CDK6 at 7q21.2 [odds ratio (OR) = 1.18, combined P add = 2.27 10(-9)] and a consistent association for rs2706748 in SH3RF1 at 4q32.3 (OR = 1.17, combined P add = 5.10 10(-6)). Interaction a

…

We found a genome-wide significant (P < 5.0 10(-8)) association for rs2282987 in CDK6 at 7q21.2 [odds ratio (OR) = 1.18, combined P add =

…
Expression profiling of ubiquitin-related genes in LKB1 mutant lung adenocarcinoma.
Wang G, Bie F, Qu X, Yang X, Liu S, Wang Y, Huang C, Wang K, Du J. Wang G, et al. Sci Rep. 2018 Sep 5;8(1):13221. doi: 10.1038/s41598-018-31592-2. Sci Rep. 2018. PMID: 30185829 Free PMC article.
Patients with LKB1 mutation and high expression of SH3RF1 had a better prognosis than the low expression group (HR 0.356, 95% CI 0.136-0.929, p = 0.035). SH3RF1 can influence cell cycle, apoptosis, DNA replication and the p53 signaling pathway. ...
Patients with LKB1 mutation and high expression of SH3RF1 had a better prognosis than the low expression group (HR 0.356, 95% CI 0.13 …
36 results