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Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets.

Newell F, Kong Y, Wilmott JS, Johansson PA, Ferguson PM, Cui C, Li Z, Kazakoff SH, Burke H, Dodds TJ, Patch AM, Nones K, Tembe V, Shang P, van der Weyden L, Wong K, Holmes O, Lo S, Leonard C, Wood S, Xu Q, Rawson RV, Mukhopadhyay P, Dummer R, Levesque MP, Jönsson G, Wang X, Yeh I, Wu H, Joseph N, Bastian BC, Long GV, Spillane AJ, Shannon KF, Thompson JF, Saw RPM, Adams DJ, Si L, Pearson JV, Hayward NK, Waddell N, Mann GJ, Guo J, Scolyer RA. Newell F, et al. Among authors: shannon kf. Nat Commun. 2019 Jul 18;10(1):3163. doi: 10.1038/s41467-019-11107-x. Nat Commun. 2019. PMID: 31320640 Free PMC article.

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Neoadjuvant dabrafenib combined with trametinib for resectable, stage IIIB-C, BRAF^V600 mutation-positive melanoma (NeoCombi): a single-arm, open-label, single-centre, phase 2 trial.

Long GV, Saw RPM, Lo S, Nieweg OE, Shannon KF, Gonzalez M, Guminski A, Lee JH, Lee H, Ferguson PM, Rawson RV, Wilmott JS, Thompson JF, Kefford RF, Ch'ng S, Stretch JR, Emmett L, Kapoor R, Rizos H, Spillane AJ, Scolyer RA, Menzies AM. Long GV, et al. Among authors: shannon kf. Lancet Oncol. 2019 Jul;20(7):961-971. doi: 10.1016/S1470-2045(19)30331-6. Epub 2019 Jun 3. Lancet Oncol. 2019. PMID: 31171444 Clinical Trial.

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Improved Risk Prediction Calculator for Sentinel Node Positivity in Patients With Melanoma: The Melanoma Institute Australia Nomogram.

Lo SN, Ma J, Scolyer RA, Haydu LE, Stretch JR, Saw RPM, Nieweg OE, Shannon KF, Spillane AJ, Ch'ng S, Mann GJ, Gershenwald JE, Thompson JF, Varey AHR. Lo SN, et al. Among authors: shannon kf. J Clin Oncol. 2020 Aug 20;38(24):2719-2727. doi: 10.1200/JCO.19.02362. Epub 2020 Jun 12. J Clin Oncol. 2020. PMID: 32530761

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Multiplex melanoma families are enriched for polygenic risk.

Law MH, Aoude LG, Duffy DL, Long GV, Johansson PA, Pritchard AL, Khosrotehrani K, Mann GJ, Montgomery GW, Iles MM, Cust AE, Palmer JM; Melanoma GWAS Consortium, Shannon KF, Spillane AJ, Stretch JR, Thompson JF, Saw RPM, Scolyer RA, Martin NG, Hayward NK, MacGregor S. Law MH, et al. Among authors: shannon kf. Hum Mol Genet. 2020 Oct 10;29(17):2976-2985. doi: 10.1093/hmg/ddaa156. Hum Mol Genet. 2020. PMID: 32716505 Free PMC article.

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Primary dermal melanoma: clinical behaviour, prognosis and treatment.

Harris CG, Lo S, Ahmed T, Scolyer RA, Ferguson PM, Karim RZ, Lam TK, Lee KK, Shannon KF, Spillane AJ, Stretch JR, Thompson JF, Saw RP. Harris CG, et al. Among authors: shannon kf. Eur J Surg Oncol. 2020 Nov;46(11):2131-2139. doi: 10.1016/j.ejso.2020.04.043. Epub 2020 May 1. Eur J Surg Oncol. 2020. PMID: 32417156

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Pre-operative ctDNA predicts survival in high-risk stage III cutaneous melanoma patients.

Lee JH, Saw RP, Thompson JF, Lo S, Spillane AJ, Shannon KF, Stretch JR, Howle J, Menzies AM, Carlino MS, Kefford RF, Long GV, Scolyer RA, Rizos H. Lee JH, et al. Among authors: shannon kf. Ann Oncol. 2019 May 1;30(5):815-822. doi: 10.1093/annonc/mdz075. Ann Oncol. 2019. PMID: 30860590 Free PMC article.

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Surgical management of the neck in patients with metastatic melanoma in parotid lymph nodes.

Den Hondt M, Starr MW, Millett MC, Smyth J, Scolyer RA, Shannon KF, Thompson JF, Ch'ng S. Den Hondt M, et al. Among authors: shannon kf. J Surg Oncol. 2019 Dec;120(8):1462-1469. doi: 10.1002/jso.25732. Epub 2019 Oct 25. J Surg Oncol. 2019. PMID: 31650567

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Reappraisal of the prognostic significance of mitotic rate supports its reincorporation into the melanoma staging system.

Kashani-Sabet M, Miller JR 3rd, Lo S, Nosrati M, Stretch JR, Shannon KF, Spillane AJ, Saw RPM, Cleaver JE, Kim KB, Leong SP, Thompson JF, Scolyer RA. Kashani-Sabet M, et al. Among authors: shannon kf. Cancer. 2020 Nov 1;126(21):4717-4725. doi: 10.1002/cncr.33088. Epub 2020 Aug 11. Cancer. 2020. PMID: 32780467

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Cumulative Incidence and Predictors of CNS Metastasis for Patients With American Joint Committee on Cancer 8th Edition Stage III Melanoma.

Haydu LE, Lo SN, McQuade JL, Amaria RN, Wargo J, Ross MI, Cormier JN, Lucci A, Lee JE, Ferguson SD, Saw RPM, Spillane AJ, Shannon KF, Stretch JR, Hwu P, Patel SP, Diab A, Wong MKK, Glitza Oliva IC, Tawbi H, Carlino MS, Menzies AM, Long GV, Lazar AJ, Tetzlaff MT, Scolyer RA, Gershenwald JE, Thompson JF, Davies MA. Haydu LE, et al. Among authors: shannon kf. J Clin Oncol. 2020 May 1;38(13):1429-1441. doi: 10.1200/JCO.19.01508. Epub 2020 Jan 28. J Clin Oncol. 2020. PMID: 31990608 Free PMC article.

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Whole genome sequencing of melanomas in adolescent and young adults reveals distinct mutation landscapes and the potential role of germline variants in disease susceptibility.

Wilmott JS, Johansson PA, Newell F, Waddell N, Ferguson P, Quek C, Patch AM, Nones K, Shang P, Pritchard AL, Kazakoff S, Holmes O, Leonard C, Wood S, Xu Q, Saw RPM, Spillane AJ, Stretch JR, Shannon KF, Kefford RF, Menzies AM, Long GV, Thompson JF, Pearson JV, Mann GJ, Hayward NK, Scolyer RA. Wilmott JS, et al. Among authors: shannon kf. Int J Cancer. 2019 Mar 1;144(5):1049-1060. doi: 10.1002/ijc.31791. Epub 2018 Nov 21. Int J Cancer. 2019. PMID: 30178487 Free article.

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