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Gemfibrozil derivatives as activators of soluble guanylyl cyclase - A structure-activity study.

Gayler KM, Quintana JM, Mattke J, Plunk MA, Kostyo JH, Karunananthan JW, Nguyen H, Shuda M, Ferreira LD, Baker H, Stinchcomb AL, Sharina I, Kane RR, Martin E. Gayler KM, et al. Among authors: sharina i. Eur J Med Chem. 2021 Nov 15;224:113729. doi: 10.1016/j.ejmech.2021.113729. Epub 2021 Aug 3. Eur J Med Chem. 2021. PMID: 34365128

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Involvement of 3',5'-cyclic inosine monophosphate in cystathionine γ-lyase-dependent regulation of the vascular tone.

Mitidieri E, Vellecco V, Brancaleone V, Vanacore D, Manzo OL, Martin E, Sharina I, Krutsenko Y, Monti MC, Morretta E, Papapetropoulos A, Caliendo G, Frecentese F, Cirino G, Sorrentino R, d'Emmanuele di Villa Bianca R, Bucci M. Mitidieri E, et al. Among authors: sharina i. Br J Pharmacol. 2021 Sep;178(18):3765-3782. doi: 10.1111/bph.15516. Epub 2021 Jun 11. Br J Pharmacol. 2021. PMID: 33931865 Free PMC article.

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RNA splicing in regulation of nitric oxide receptor soluble guanylyl cyclase.

Sharina IG, Cote GJ, Martin E, Doursout MF, Murad F. Sharina IG, et al. Nitric Oxide. 2011 Oct 30;25(3):265-74. doi: 10.1016/j.niox.2011.08.001. Epub 2011 Aug 16. Nitric Oxide. 2011. PMID: 21867767 Free PMC article. Review.

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A short history of cGMP, guanylyl cyclases, and cGMP-dependent protein kinases.

Kots AY, Martin E, Sharina IG, Murad F. Kots AY, et al. Among authors: sharina ig. Handb Exp Pharmacol. 2009;(191):1-14. doi: 10.1007/978-3-540-68964-5_1. Handb Exp Pharmacol. 2009. PMID: 19089322 Free PMC article. Review.

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Higher susceptibility to heme oxidation and lower protein stability of the rare α₁C517Yβ₁ sGC variant associated with moyamoya syndrome.

Sharina I, Lezgyieva K, Krutsenko Y, Martin E. Sharina I, et al. Biochem Pharmacol. 2021 Apr;186:114459. doi: 10.1016/j.bcp.2021.114459. Epub 2021 Feb 8. Biochem Pharmacol. 2021. PMID: 33571505 Free PMC article.

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The Role of Reactive Oxygen and Nitrogen Species in the Expression and Splicing of Nitric Oxide Receptor.

Sharina IG, Martin E. Sharina IG, et al. Antioxid Redox Signal. 2017 Jan 20;26(3):122-136. doi: 10.1089/ars.2016.6687. Epub 2016 Apr 19. Antioxid Redox Signal. 2017. PMID: 26972233 Free PMC article. Review.

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FoxO4 controls sGCβ transcription in vascular smooth muscle.

Galley JC, Miller MP, Sanker S, Liu M, Sharina I, Martin E, Gomez D, Straub AC. Galley JC, et al. Among authors: sharina i. Am J Physiol Heart Circ Physiol. 2022 Mar 1;322(3):H417-H426. doi: 10.1152/ajpheart.00551.2021. Epub 2022 Jan 28. Am J Physiol Heart Circ Physiol. 2022. PMID: 35089807

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Homogeneous single-label cGMP detection platform for the functional study of nitric oxide-sensitive (soluble) guanylyl cyclases and cGMP-specific phosphodiesterases.

Kopra K, Sharina I, Martin E, Härmä H. Kopra K, et al. Among authors: sharina i. Sci Rep. 2020 Oct 15;10(1):17469. doi: 10.1038/s41598-020-74611-x. Sci Rep. 2020. PMID: 33060787 Free PMC article.

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Regulation of soluble guanylyl cyclase redox state by hydrogen sulfide.

Zhou Z, Martin E, Sharina I, Esposito I, Szabo C, Bucci M, Cirino G, Papapetropoulos A. Zhou Z, et al. Among authors: sharina i. Pharmacol Res. 2016 Sep;111:556-562. doi: 10.1016/j.phrs.2016.06.029. Epub 2016 Jul 1. Pharmacol Res. 2016. PMID: 27378567 Free PMC article.

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Frequency of Tongue Cleaning Impacts the Human Tongue Microbiome Composition and Enterosalivary Circulation of Nitrate.

Tribble GD, Angelov N, Weltman R, Wang BY, Eswaran SV, Gay IC, Parthasarathy K, Dao DV, Richardson KN, Ismail NM, Sharina IG, Hyde ER, Ajami NJ, Petrosino JF, Bryan NS. Tribble GD, et al. Among authors: sharina ig. Front Cell Infect Microbiol. 2019 Mar 1;9:39. doi: 10.3389/fcimb.2019.00039. eCollection 2019. Front Cell Infect Microbiol. 2019. PMID: 30881924 Free PMC article.

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