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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1978 1
1979 2
1980 1
1984 1
1986 2
1990 1
1991 2
1994 1
1995 7
1996 2
1997 3
1998 1
1999 1
2000 3
2001 1
2005 4
2006 2
2008 1
2010 1
2011 2
2012 1
2013 3
2014 3
2015 5
2016 4
2017 2
2018 4
2019 1
2024 0

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58 results

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Page 1
Molecular Basis of Valine-Citrulline-PABC Linker Instability in Site-Specific ADCs and Its Mitigation by Linker Design.
Dorywalska M, Dushin R, Moine L, Farias SE, Zhou D, Navaratnam T, Lui V, Hasa-Moreno A, Casas MG, Tran TT, Delaria K, Liu SH, Foletti D, O'Donnell CJ, Pons J, Shelton DL, Rajpal A, Strop P. Dorywalska M, et al. Among authors: shelton dl. Mol Cancer Ther. 2016 May;15(5):958-70. doi: 10.1158/1535-7163.MCT-15-1004. Epub 2016 Mar 4. Mol Cancer Ther. 2016. PMID: 26944918
RN927C, a Site-Specific Trop-2 Antibody-Drug Conjugate (ADC) with Enhanced Stability, Is Highly Efficacious in Preclinical Solid Tumor Models.
Strop P, Tran TT, Dorywalska M, Delaria K, Dushin R, Wong OK, Ho WH, Zhou D, Wu A, Kraynov E, Aschenbrenner L, Han B, O'Donnell CJ, Pons J, Rajpal A, Shelton DL, Liu SH. Strop P, et al. Among authors: shelton dl. Mol Cancer Ther. 2016 Nov;15(11):2698-2708. doi: 10.1158/1535-7163.MCT-16-0431. Epub 2016 Aug 31. Mol Cancer Ther. 2016. PMID: 27582525
Novel class of pain drugs based on antagonism of NGF.
Hefti FF, Rosenthal A, Walicke PA, Wyatt S, Vergara G, Shelton DL, Davies AM. Hefti FF, et al. Among authors: shelton dl. Trends Pharmacol Sci. 2006 Feb;27(2):85-91. doi: 10.1016/j.tips.2005.12.001. Epub 2005 Dec 27. Trends Pharmacol Sci. 2006. PMID: 16376998 Review.
Site-specific conjugation improves therapeutic index of antibody drug conjugates with high drug loading.
Strop P, Delaria K, Foletti D, Witt JM, Hasa-Moreno A, Poulsen K, Casas MG, Dorywalska M, Farias S, Pios A, Lui V, Dushin R, Zhou D, Navaratnam T, Tran TT, Sutton J, Lindquist KC, Han B, Liu SH, Shelton DL, Pons J, Rajpal A. Strop P, et al. Among authors: shelton dl. Nat Biotechnol. 2015 Jul;33(7):694-6. doi: 10.1038/nbt.3274. Nat Biotechnol. 2015. PMID: 26154005 No abstract available.
Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates.
Costa MJ, Kudaravalli J, Ma JT, Ho WH, Delaria K, Holz C, Stauffer A, Chunyk AG, Zong Q, Blasi E, Buetow B, Tran TT, Lindquist K, Dorywalska M, Rajpal A, Shelton DL, Strop P, Liu SH. Costa MJ, et al. Among authors: shelton dl. Sci Rep. 2019 Feb 21;9(1):2443. doi: 10.1038/s41598-019-38745-x. Sci Rep. 2019. PMID: 30792442 Free PMC article.
Tanezumab for the treatment of pain from osteoarthritis of the knee.
Lane NE, Schnitzer TJ, Birbara CA, Mokhtarani M, Shelton DL, Smith MD, Brown MT. Lane NE, et al. Among authors: shelton dl. N Engl J Med. 2010 Oct 14;363(16):1521-31. doi: 10.1056/NEJMoa0901510. Epub 2010 Sep 29. N Engl J Med. 2010. PMID: 20942668 Free PMC article. Clinical Trial.
Artemin has potent neurotrophic actions on injured C-fibres.
Bennett DL, Boucher TJ, Michael GJ, Popat RJ, Malcangio M, Averill SA, Poulsen KT, Priestley JV, Shelton DL, McMahon SB. Bennett DL, et al. Among authors: shelton dl. J Peripher Nerv Syst. 2006 Dec;11(4):330-45. doi: 10.1111/j.1529-8027.2006.00106.x. J Peripher Nerv Syst. 2006. PMID: 17117942
58 results