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1990 2
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Page 1
Development of 2,2-dimethylchromanol cysteinyl LT1 receptor antagonists.
Chambers RJ, Antognoli GW, Cheng JB, Kuperman AV, Liston TC, Marfat A, Owens BS, Pillar JS, Shirley JT, Watson JW. Chambers RJ, et al. Among authors: shirley jt. Bioorg Med Chem Lett. 1998 Dec 15;8(24):3577-82. doi: 10.1016/s0960-894x(98)00654-4. Bioorg Med Chem Lett. 1998. PMID: 9934474
N-carbamoyl analogs of Zafirlukast: potent receptor antagonists of leukotriene D4.
Brown MF, Marfat A, Antognoli G, Chambers RJ, Cheng JB, Damon DB, Liston TE, McGlynn MA, O'Sullivan SP, Owens BS, Pillar JS, Shirley JT, Watson JW. Brown MF, et al. Among authors: shirley jt. Bioorg Med Chem Lett. 1998 Sep 22;8(18):2451-6. doi: 10.1016/s0960-894x(98)00442-9. Bioorg Med Chem Lett. 1998. PMID: 9873560
A new chemical tool for exploring the role of the PDE4D isozyme in leukocyte function.
Chambers RJ, Abrams K, Castleberry TA, Cheng JB, Fisher DA, Kamath AV, Marfat A, Nettleton DO, Pillar JD, Salter ED, Sheils AL, Shirley JT, Turner CR, Umland JP, Lam KT. Chambers RJ, et al. Among authors: shirley jt. Bioorg Med Chem Lett. 2006 Feb;16(3):718-21. doi: 10.1016/j.bmcl.2005.10.026. Epub 2005 Nov 2. Bioorg Med Chem Lett. 2006. PMID: 16263279
Striking effect of hydroxamic acid substitution on the phosphodiesterase type 4 (PDE4) and TNF alpha inhibitory activity of two series of rolipram analogues: implications for a new active site model of PDE4.
Kleinman EF, Campbell E, Giordano LA, Cohan VL, Jenkinson TH, Cheng JB, Shirley JT, Pettipher ER, Salter ED, Hibbs TA, DiCapua FM, Bordner J. Kleinman EF, et al. Among authors: shirley jt. J Med Chem. 1998 Jan 29;41(3):266-70. doi: 10.1021/jm970685m. J Med Chem. 1998. PMID: 9464356 No abstract available.
Biarylcarboxylic acids and -amides: inhibition of phosphodiesterase type IV versus [3H]rolipram binding activity and their relationship to emetic behavior in the ferret.
Duplantier AJ, Biggers MS, Chambers RJ, Cheng JB, Cooper K, Damon DB, Eggler JF, Kraus KG, Marfat A, Masamune H, Pillar JS, Shirley JT, Umland JP, Watson JW. Duplantier AJ, et al. Among authors: shirley jt. J Med Chem. 1996 Jan 5;39(1):120-5. doi: 10.1021/jm9505066. J Med Chem. 1996. PMID: 8568798
11 results