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IL-6/IL-6R axis plays a critical role in acute kidney injury.
Nechemia-Arbely Y, Barkan D, Pizov G, Shriki A, Rose-John S, Galun E, Axelrod JH. Nechemia-Arbely Y, et al. Among authors: shriki a. J Am Soc Nephrol. 2008 Jun;19(6):1106-15. doi: 10.1681/ASN.2007070744. Epub 2008 Mar 12. J Am Soc Nephrol. 2008. PMID: 18337485 Free PMC article.
Interleukin 6-dependent genomic instability heralds accelerated carcinogenesis following liver regeneration on a background of chronic hepatitis.
Lanton T, Shriki A, Nechemia-Arbely Y, Abramovitch R, Levkovitch O, Adar R, Rosenberg N, Paldor M, Goldenberg D, Sonnenblick A, Peled A, Rose-John S, Galun E, Axelrod JH. Lanton T, et al. Among authors: shriki a. Hepatology. 2017 May;65(5):1600-1611. doi: 10.1002/hep.29004. Epub 2017 Mar 23. Hepatology. 2017. PMID: 28027584
Tissue microarray-based study of patients with lymph node-positive breast cancer shows tyrosine phosphorylation of signal transducer and activator of transcription 3 (tyrosine705-STAT3) is a marker of good prognosis.
Sonnenblick A, Shriki A, Galun E, Axelrod JH, Daum H, Rottenberg Y, Hamburger T, Mali B, Peretz T. Sonnenblick A, et al. Among authors: shriki a. Clin Transl Oncol. 2012 Mar;14(3):232-6. doi: 10.1007/s12094-012-0789-z. Clin Transl Oncol. 2012. PMID: 22374428
In vivo evidence suggesting reciprocal renal hypoxia-inducible factor-1 upregulation and signal transducer and activator of transcription 3 activation in response to hypoxic and non-hypoxic stimuli.
Nechemia-Arbely Y, Khamaisi M, Rosenberger C, Koesters R, Shina A, Geva C, Shriki A, Klaus S, Rosen S, Rose-John S, Galun E, Axelrod JH, Heyman SN. Nechemia-Arbely Y, et al. Among authors: shriki a. Clin Exp Pharmacol Physiol. 2013 Apr;40(4):262-72. doi: 10.1111/1440-1681.12064. Clin Exp Pharmacol Physiol. 2013. PMID: 23384058