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Heteromeric canonical transient receptor potential 1 and 4 channels play a critical role in epileptiform burst firing and seizure-induced neurodegeneration.
Phelan KD, Mock MM, Kretz O, Shwe UT, Kozhemyakin M, Greenfield LJ, Dietrich A, Birnbaumer L, Freichel M, Flockerzi V, Zheng F. Phelan KD, et al. Among authors: shwe ut. Mol Pharmacol. 2012 Mar;81(3):384-92. doi: 10.1124/mol.111.075341. Epub 2011 Dec 5. Mol Pharmacol. 2012. PMID: 22144671 Free PMC article.