Sigmond J[au] - Search Results

Year	Number of Results
2003	1
2004	3
2005	2
2006	2
2007	2
2008	2
2009	1
2010	2
2022	0

1

Pyrimidine and purine analogues, effects on cell cycle regulation and the role of cell cycle inhibitors to enhance their cytotoxicity.

Sigmond J, Peters GJ. Sigmond J, et al. Nucleosides Nucleotides Nucleic Acids. 2005;24(10-12):1997-2022. doi: 10.1080/15257770500269556. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438061 Review.

2

Pharmacological aspects of the enzastaurin-pemetrexed combination in non-small cell lung cancer (NSCLC).

Giovannetti E, Honeywell R, Hanauske AR, Tekle C, Kuenen B, Sigmond J, Giaccone G, Peters GJ. Giovannetti E, et al. Among authors: sigmond j. Curr Drug Targets. 2010 Jan;11(1):12-28. doi: 10.2174/138945010790031009. Curr Drug Targets. 2010. PMID: 19839931 Review.

3

Synthesis and biological activity of a gemcitabine phosphoramidate prodrug.

Wu W, Sigmond J, Peters GJ, Borch RF. Wu W, et al. Among authors: sigmond j. J Med Chem. 2007 Jul 26;50(15):3743-6. doi: 10.1021/jm070269u. Epub 2007 Jun 29. J Med Chem. 2007. PMID: 17602464 Free PMC article.

4

Gemcitabine uptake in glioblastoma multiforme: potential as a radiosensitizer.

Sigmond J, Honeywell RJ, Postma TJ, Dirven CM, de Lange SM, van der Born K, Laan AC, Baayen JC, Van Groeningen CJ, Bergman AM, Giaccone G, Peters GJ. Sigmond J, et al. Ann Oncol. 2009 Jan;20(1):182-7. doi: 10.1093/annonc/mdn543. Epub 2008 Aug 12. Ann Oncol. 2009. PMID: 18701427 Free article. Clinical Trial.

5

Immunocytochemical detection of deoxycytidine kinase in haematological malignancies and solid tumours.

Hubeek I, Peters GJ, Broekhuizen AJ, Talianidis I, Sigmond J, Gibson BE, Creutzig U, Giaccone G, Kaspers GJ. Hubeek I, et al. Among authors: sigmond j. J Clin Pathol. 2005 Jul;58(7):695-9. doi: 10.1136/jcp.2004.023861. J Clin Pathol. 2005. PMID: 15976334 Free PMC article.

6

Staurosporine increases toxicity of gemcitabine in non-small cell lung cancer cells: role of protein kinase C, deoxycytidine kinase and ribonucleotide reductase.

Sigmond J, Bergman AM, Leon LG, Loves WJ, Hoebe EK, Peters GJ. Sigmond J, et al. Anticancer Drugs. 2010 Jul;21(6):591-9. doi: 10.1097/CAD.0b013e32833a3543. Anticancer Drugs. 2010. PMID: 20436341

7

Combinations of 5-fluorouracil with UCN-01 or staurosporine.

Sigmond J, Comijn EM, Kamphuis JA, Peters GJ. Sigmond J, et al. Nucleosides Nucleotides Nucleic Acids. 2004 Oct;23(8-9):1503-6. doi: 10.1081/NCN-200027718. Nucleosides Nucleotides Nucleic Acids. 2004. PMID: 15571286

8

Molecular pathways involved in the synergistic interaction of the PKC beta inhibitor enzastaurin with the antifolate pemetrexed in non-small cell lung cancer cells.

Tekle C, Giovannetti E, Sigmond J, Graff JR, Smid K, Peters GJ. Tekle C, et al. Among authors: sigmond j. Br J Cancer. 2008 Sep 2;99(5):750-9. doi: 10.1038/sj.bjc.6604566. Epub 2008 Aug 19. Br J Cancer. 2008. PMID: 18728666 Free PMC article.

9

Time course of enhanced activity of deoxycytidine kinase and thymidine kinase 1 and 2 in cultured human squamous lung carcinoma cells, SW-1573, induced by gamma-irradiation.

Haveman J, Sigmond J, van Bree C, Franken NA, Koedooder C, Peters GJ. Haveman J, et al. Among authors: sigmond j. Oncol Rep. 2006 Oct;16(4):901-5. doi: 10.3892/or.16.4.901. Oncol Rep. 2006. PMID: 16969512

10

Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression.

Sigmond J, Backus HH, Wouters D, Temmink OH, Jansen G, Peters GJ. Sigmond J, et al. Biochem Pharmacol. 2003 Aug 1;66(3):431-8. doi: 10.1016/s0006-2952(03)00287-9. Biochem Pharmacol. 2003. PMID: 12907242

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