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2'-O-Methylation of the second transcribed nucleotide within the mRNA 5' cap impacts the protein production level in a cell-specific manner and contributes to RNA immune evasion.
Drazkowska K, Tomecki R, Warminski M, Baran N, Cysewski D, Depaix A, Kasprzyk R, Kowalska J, Jemielity J, Sikorski PJ. Drazkowska K, et al. Among authors: sikorski pj. Nucleic Acids Res. 2022 Sep 9;50(16):9051-9071. doi: 10.1093/nar/gkac722. Nucleic Acids Res. 2022. PMID: 36018811 Free PMC article.
Applications of Phosphate Modification and Labeling to Study (m)RNA Caps.
Warminski M, Sikorski PJ, Kowalska J, Jemielity J. Warminski M, et al. Among authors: sikorski pj. Top Curr Chem (Cham). 2017 Feb;375(1):16. doi: 10.1007/s41061-017-0106-y. Epub 2017 Jan 23. Top Curr Chem (Cham). 2017. PMID: 28116583 Free PMC article. Review.
RNA Ligation for Mono and Dually Labeled RNAs.
Depaix A, Mlynarska-Cieslak A, Warminski M, Sikorski PJ, Jemielity J, Kowalska J. Depaix A, et al. Among authors: sikorski pj. Chemistry. 2021 Aug 19;27(47):12190-12197. doi: 10.1002/chem.202101909. Epub 2021 Jul 5. Chemistry. 2021. PMID: 34114681
Trinucleotide mRNA Cap Analogue N6-Benzylated at the Site of Posttranscriptional m6Am Mark Facilitates mRNA Purification and Confers Superior Translational Properties In Vitro and In Vivo.
Warminski M, Trepkowska E, Smietanski M, Sikorski PJ, Baranowski MR, Bednarczyk M, Kedzierska H, Majewski B, Mamot A, Papiernik D, Popielec A, Serwa RA, Shimanski BA, Sklepkiewicz P, Sklucka M, Sokolowska O, Spiewla T, Toczydlowska-Socha D, Warminska Z, Wolosewicz K, Zuberek J, Mugridge JS, Nowis D, Golab J, Jemielity J, Kowalska J. Warminski M, et al. Among authors: sikorski pj. J Am Chem Soc. 2024 Mar 27;146(12):8149-8163. doi: 10.1021/jacs.3c12629. Epub 2024 Mar 5. J Am Chem Soc. 2024. PMID: 38442005 Free PMC article.
28 results