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Urinary proteins detected using modern proteomics intervene in early type 2 diabetic kidney disease - a pilot study.
Golea-Secara A, Munteanu C, Sarbu M, Cretu OM, Velciov S, Vlad A, Bob F, Gadalean F, Gluhovschi C, Milas O, Simulescu A, Mogos-Stefan M, Patruica M, Petrica L, Zamfir AD. Golea-Secara A, et al. Among authors: simulescu a. Biomark Med. 2020 Nov;14(16):1521-1536. doi: 10.2217/bmm-2020-0308. Epub 2020 Oct 22. Biomark Med. 2020. PMID: 33090017
Long noncoding RNAs may impact podocytes and proximal tubule function through modulating miRNAs expression in Early Diabetic Kidney Disease of Type 2 Diabetes Mellitus patients.
Petrica L, Hogea E, Gadalean F, Vlad A, Vlad M, Dumitrascu V, Velciov S, Gluhovschi C, Bob F, Ursoniu S, Jianu DC, Matusz P, Pusztai AM, Motoc A, Cretu OM, Radu D, Milas O, Golea-Secara A, Simulescu A, Mogos-Stefan M, Patruica M, Balint L, Ienciu S, Vlad D, Popescu R. Petrica L, et al. Among authors: simulescu a. Int J Med Sci. 2021 Mar 15;18(10):2093-2101. doi: 10.7150/ijms.56551. eCollection 2021. Int J Med Sci. 2021. PMID: 33859515 Free PMC article.
MiRNA Expression is Associated with Clinical Variables Related to Vascular Remodeling in the Kidney and the Brain in Type 2 Diabetes Mellitus Patients.
Petrica L, Pusztai AM, Vlad M, Vlad A, Gadalean F, Dumitrascu V, Vlad D, Velciov S, Gluhovschi C, Bob F, Ursoniu S, Petrica M, Matusz P, Cretu O, Radu D, Milas O, Secara A, Simulescu A, Popescu R, Jianu DC. Petrica L, et al. Among authors: simulescu a. Endocr Res. 2020 Feb-May;45(2):119-130. doi: 10.1080/07435800.2019.1690505. Epub 2019 Nov 14. Endocr Res. 2020. PMID: 31724439
Interleukins and miRNAs intervene in the early stages of diabetic kidney disease in Type 2 diabetes mellitus patients.
Petrica L, Milas O, Vlad M, Vlad A, Gadalean F, Dumitrascu V, Velciov S, Gluhovschi C, Bob F, Ursoniu S, Jianu DC, Matusz P, Pusztai AM, Cretu O, Radu D, Secara A, Simulescu A, Stefan M, Popescu R, Vlad D. Petrica L, et al. Among authors: simulescu a. Biomark Med. 2019 Dec;13(18):1577-1588. doi: 10.2217/bmm-2019-0124. Epub 2019 Oct 30. Biomark Med. 2019. PMID: 31663375
Deregulated profiles of urinary microRNAs may explain podocyte injury and proximal tubule dysfunction in normoalbuminuric patients with type 2 diabetes mellitus.
Milas O, Gadalean F, Vlad A, Dumitrascu V, Gluhovschi C, Gluhovschi G, Velciov S, Popescu R, Bob F, Matusz P, Pusztai AM, Cretu OM, Secara A, Simulescu A, Ursoniu S, Vlad D, Petrica L. Milas O, et al. Among authors: simulescu a. J Investig Med. 2018 Apr;66(4):747-754. doi: 10.1136/jim-2017-000556. Epub 2017 Dec 25. J Investig Med. 2018. PMID: 29279420
Therapy with atorvastatin versus rosuvastatin reduces urinary podocytes, podocyte-associated molecules, and proximal tubule dysfunction biomarkers in patients with type 2 diabetes mellitus: a pilot study.
Vlad A, Vlad M, Petrica L, Ursoniu S, Gadalean F, Popescu R, Vlad D, Dumitrascu V, Gluhovschi G, Gluhovschi C, Velciov S, Bob F, Matusz P, Secara A, Simulescu A, Jianu DC. Vlad A, et al. Among authors: simulescu a. Ren Fail. 2017 Nov;39(1):112-119. doi: 10.1080/0886022X.2016.1254657. Epub 2016 Nov 13. Ren Fail. 2017. PMID: 27841047 Free PMC article. Clinical Trial.
Urinary podocyte-associated mRNA levels correlate with proximal tubule dysfunction in early diabetic nephropathy of type 2 diabetes mellitus.
Petrica L, Ursoniu S, Gadalean F, Vlad A, Gluhovschi G, Dumitrascu V, Vlad D, Gluhovschi C, Velciov S, Bob F, Matusz P, Milas O, Secara A, Simulescu A, Popescu R. Petrica L, et al. Among authors: simulescu a. Diabetol Metab Syndr. 2017 May 6;9:31. doi: 10.1186/s13098-017-0228-y. eCollection 2017. Diabetol Metab Syndr. 2017. PMID: 28484521 Free PMC article.
Pro-inflammatory cytokines are associated with podocyte damage and proximal tubular dysfunction in the early stage of diabetic kidney disease in type 2 diabetes mellitus patients.
Milas O, Gadalean F, Vlad A, Dumitrascu V, Velciov S, Gluhovschi C, Bob F, Popescu R, Ursoniu S, Jianu DC, Matusz P, Pusztai AM, Secara A, Simulescu A, Stefan M, Patruica M, Petrica F, Vlad D, Petrica L. Milas O, et al. Among authors: simulescu a. J Diabetes Complications. 2020 Feb;34(2):107479. doi: 10.1016/j.jdiacomp.2019.107479. Epub 2019 Nov 5. J Diabetes Complications. 2020. PMID: 31806428