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Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer.
Pingili AK, Chaib M, Sipe LM, Miller EJ, Teng B, Sharma R, Yarbro JR, Asemota S, Al Abdallah Q, Mims TS, Marion TN, Daria D, Sekhri R, Hamilton AM, Troester MA, Jo H, Choi HY, Hayes DN, Cook KL, Narayanan R, Pierre JF, Makowski L. Pingili AK, et al. Among authors: sipe lm. Cell Rep. 2021 Jun 22;35(12):109285. doi: 10.1016/j.celrep.2021.109285. Cell Rep. 2021. PMID: 34161764 Free PMC article.
Protein kinase C delta regulates mononuclear phagocytes and hinders response to immunotherapy in cancer.
Chaib M, Holt JR, Fisher EL, Sipe LM, Bohm MS, Joseph SC, Simmons BW, Eugin Simon S, Yarbro JR, Tanveer U, Halle JL, Carson JA, Hollingsworth TJ, Wei Q, Rathmell JC, Thomas PG, Hayes DN, Makowski L. Chaib M, et al. Among authors: sipe lm. Sci Adv. 2023 Dec 22;9(51):eadd3231. doi: 10.1126/sciadv.add3231. Epub 2023 Dec 22. Sci Adv. 2023. PMID: 38134280 Free PMC article.
PKC agonism restricts innate immune suppression, promotes antigen cross-presentation and synergizes with agonistic CD40 antibody therapy to activate CD8+ T cells in breast cancer.
Chaib M, Sipe LM, Yarbro JR, Bohm MS, Counts BR, Tanveer U, Pingili AK, Daria D, Marion TN, Carson JA, Thomas PG, Makowski L. Chaib M, et al. Among authors: sipe lm. Cancer Lett. 2022 Apr 10;531:98-108. doi: 10.1016/j.canlet.2022.01.017. Epub 2022 Jan 21. Cancer Lett. 2022. PMID: 35074498 Free PMC article.
FXR Agonism with Bile Acid Mimetic Reduces Pre-Clinical Triple-Negative Breast Cancer Burden.
Joseph SC, Eugin Simon S, Bohm MS, Kim M, Pye ME, Simmons BW, Graves DG, Thomas-Gooch SM, Tanveer UA, Holt JR, Ponnusamy S, Sipe LM, Hayes DN, Cook KL, Narayanan R, Pierre JF, Makowski L. Joseph SC, et al. Among authors: sipe lm. Cancers (Basel). 2024 Mar 30;16(7):1368. doi: 10.3390/cancers16071368. Cancers (Basel). 2024. PMID: 38611046 Free PMC article.