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Targeting the nucleolus as a therapeutic strategy in human disease.
Corman A, Sirozh O, Lafarga V, Fernandez-Capetillo O. Corman A, et al. Among authors: sirozh o. Trends Biochem Sci. 2023 Mar;48(3):274-287. doi: 10.1016/j.tibs.2022.09.006. Epub 2022 Oct 10. Trends Biochem Sci. 2023. PMID: 36229381 Free article. Review.
Activation of the integrated stress response is a vulnerability for multidrug-resistant FBXW7-deficient cells.
Sanchez-Burgos L, Navarro-González B, García-Martín S, Sirozh O, Mota-Pino J, Fueyo-Marcos E, Tejero H, Antón ME, Murga M, Al-Shahrour F, Fernandez-Capetillo O. Sanchez-Burgos L, et al. Among authors: sirozh o. EMBO Mol Med. 2022 Sep 7;14(9):e15855. doi: 10.15252/emmm.202215855. Epub 2022 Jul 21. EMBO Mol Med. 2022. PMID: 35861150 Free PMC article.
Widespread displacement of DNA- and RNA-binding factors underlies toxicity of arginine-rich cell-penetrating peptides.
Lafarga V, Sirozh O, Díaz-López I, Galarreta A, Hisaoka M, Zarzuela E, Boskovic J, Jovanovic B, Fernandez-Leiro R, Muñoz J, Stoecklin G, Ventoso I, Fernandez-Capetillo O. Lafarga V, et al. Among authors: sirozh o. EMBO J. 2021 Jul 1;40(13):e103311. doi: 10.15252/embj.2019103311. Epub 2021 May 12. EMBO J. 2021. PMID: 33978236 Free PMC article.