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Colony stimulating factor-1 producing endothelial cells and mesenchymal stromal cells maintain monocytes within a perivascular bone marrow niche.
Emoto T, Lu J, Sivasubramaniyam T, Maan H, Khan AB, Abow AA, Schroer SA, Hyduk SJ, Althagafi MG, McKee TD, Fu F, Shabro S, Ulndreaj A, Chiu F, Paneda E, Pacheco S, Wang T, Li A, Jiang JX, Libby P, Husain M, Wang B, Rubin BB, Cybulsky MI, Robbins CS. Emoto T, et al. Among authors: sivasubramaniyam t. Immunity. 2022 May 10;55(5):862-878.e8. doi: 10.1016/j.immuni.2022.04.005. Epub 2022 May 3. Immunity. 2022. PMID: 35508166 Free article.
Single-Cell RNA Sequencing Reveals a Distinct Immune Landscape of Myeloid Cells in Coronary Culprit Plaques Causing Acute Coronary Syndrome.
Emoto T, Yamamoto H, Yamashita T, Takaya T, Sawada T, Takeda S, Taniguchi M, Sasaki N, Yoshida N, Saito Y, Sivasubramaniyam T, Otake H, Furuyashiki T, Robbins CS, Kawai H, Hirata KI. Emoto T, et al. Among authors: sivasubramaniyam t. Circulation. 2022 May 3;145(18):1434-1436. doi: 10.1161/CIRCULATIONAHA.121.058414. Epub 2022 May 2. Circulation. 2022. PMID: 35500048 No abstract available.
Dual Role of Caspase 8 in Adipocyte Apoptosis and Metabolic Inflammation.
Luk CT, Chan CK, Chiu F, Shi SY, Misra PS, Li YZ, Pollock-Tahiri E, Schroer SA, Desai HR, Sivasubramaniyam T, Cai EP, Krishnamurthy M, Han DJ, Chowdhury A, Aslam R, Yuen DA, Hakem A, Hakem R, Woo M. Luk CT, et al. Among authors: sivasubramaniyam t. Diabetes. 2023 Dec 1;72(12):1751-1765. doi: 10.2337/db22-1033. Diabetes. 2023. PMID: 37699387
Macrophage Jak2 deficiency accelerates atherosclerosis through defects in cholesterol efflux.
Dotan I, Yang J, Ikeda J, Roth Z, Pollock-Tahiri E, Desai H, Sivasubramaniyam T, Rehal S, Rapps J, Li YZ, Le H, Farber G, Alchami E, Xiao C, Karim S, Gronda M, Saikali MF, Tirosh A, Wagner KU, Genest J, Schimmer AD, Gupta V, Minden MD, Cummins CL, Lewis GF, Robbins C, Jongstra-Bilen J, Cybulsky M, Woo M. Dotan I, et al. Among authors: sivasubramaniyam t. Commun Biol. 2022 Feb 15;5(1):132. doi: 10.1038/s42003-022-03078-5. Commun Biol. 2022. PMID: 35169231 Free PMC article.
Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation.
Desai HR, Sivasubramaniyam T, Revelo XS, Schroer SA, Luk CT, Rikkala PR, Metherel AH, Dodington DW, Park YJ, Kim MJ, Rapps JA, Besla R, Robbins CS, Wagner KU, Bazinet RP, Winer DA, Woo M. Desai HR, et al. Among authors: sivasubramaniyam t. Sci Rep. 2017 Aug 9;7(1):7653. doi: 10.1038/s41598-017-07923-0. Sci Rep. 2017. PMID: 28794431 Free PMC article.
JAK2-IGF1 axis in osteoclasts regulates postnatal growth in mice.
Dodington DW, Yumol JL, Yang J, Pollock-Tahiri E, Sivasubramaniyam T, Sacco SM, Schroer SA, Li YE, Le H, Ward WE, Woo M. Dodington DW, et al. Among authors: sivasubramaniyam t. JCI Insight. 2021 Mar 8;6(5):e137045. doi: 10.1172/jci.insight.137045. JCI Insight. 2021. PMID: 33682794 Free PMC article.
Dj1 deficiency protects against atherosclerosis with anti-inflammatory response in macrophages.
Sivasubramaniyam T, Yang J, Cheng HS, Zyla A, Li A, Besla R, Dotan I, Revelo XS, Shi SY, Le H, Schroer SA, Dodington DW, Park YJ, Kim MJ, Febbraro D, Ruel I, Genest J, Kim RH, Mak TW, Winer DA, Robbins CS, Woo M. Sivasubramaniyam T, et al. Sci Rep. 2021 Feb 25;11(1):4723. doi: 10.1038/s41598-021-84063-6. Sci Rep. 2021. PMID: 33633277 Free PMC article.
Hepatic JAK2 protects against atherosclerosis through circulating IGF-1.
Sivasubramaniyam T, Schroer SA, Li A, Luk CT, Shi SY, Besla R, Dodington DW, Metherel AH, Kitson AP, Brunt JJ, Lopes J, Wagner KU, Bazinet RP, Bendeck MP, Robbins CS, Woo M. Sivasubramaniyam T, et al. JCI Insight. 2017 Jul 20;2(14):e93735. doi: 10.1172/jci.insight.93735. eCollection 2017 Jul 20. JCI Insight. 2017. PMID: 28724798 Free PMC article.
21 results