Skiles G[au] - Search Results

Year	Number of Results
1989	1
1991	2
1992	1
1993	2
1996	2
1997	2
1998	1
2001	2
2004	1
2006	1
2007	2
2008	4
2009	1
2010	1
2011	3
2012	1
2013	1
2014	1
2016	2
2017	1
2018	1
2023	0

1

Clinical Pharmacokinetics and Pharmacodynamics of Etelcalcetide, a Novel Calcimimetic for Treatment of Secondary Hyperparathyroidism in Patients With Chronic Kidney Disease on Hemodialysis.

Wu B, Melhem M, Subramanian R, Chen P, Jaramilla Sloey B, Fouqueray B, Hock MB, Skiles GL, Chow AT, Lee E. Wu B, et al. Among authors: skiles gl. J Clin Pharmacol. 2018 Jun;58(6):717-726. doi: 10.1002/jcph.1090. Epub 2018 Mar 13. J Clin Pharmacol. 2018. PMID: 29534286 Review.

2

Determination of Etelcalcetide Biotransformation and Hemodialysis Kinetics to Guide the Timing of Its Dosing.

Edson KZ, Wu BM, Iyer A, Goodman W, Skiles GL, Subramanian R. Edson KZ, et al. Among authors: skiles gl. Kidney Int Rep. 2016 Apr 21;1(1):24-33. doi: 10.1016/j.ekir.2016.04.002. eCollection 2016 May. Kidney Int Rep. 2016. PMID: 29318205 Free PMC article.

3

Detection and characterization of DNA adducts of 3-methylindole.

Regal KA, Laws GM, Yuan C, Yost GS, Skiles GL. Regal KA, et al. Among authors: skiles gl. Chem Res Toxicol. 2001 Aug;14(8):1014-24. doi: 10.1021/tx0100237. Chem Res Toxicol. 2001. PMID: 11511175

4

P450-mediated O-demethylated metabolite is responsible for rat hepatobiliary toxicity of pyridyltriazine-containing PI3K inhibitors.

Subramanian R, Aidasani D, Bailey K, Branstetter D, Everds N, Jiang J, Norman MH, Primack R, Skiles GL, Soto I, Stec MM, Wagner M, Wu T, Zhu X, Lebrec H. Subramanian R, et al. Among authors: skiles gl. Toxicol Sci. 2014 Nov;142(1):298-310. doi: 10.1093/toxsci/kfu178. Epub 2014 Aug 26. Toxicol Sci. 2014. PMID: 25159132

5

A novel biotransformation of alkyl aminopyrrolidine to aminopiperidine ring by human CYP3A.

Chen Y, Skiles GL, Shou M, Hickman D, Hsieh F. Chen Y, et al. Among authors: skiles gl. Drug Metab Dispos. 2011 Sep;39(9):1668-73. doi: 10.1124/dmd.111.039750. Epub 2011 Jun 14. Drug Metab Dispos. 2011. PMID: 21673127

6

Mechanistic studies on the cytochrome P450-catalyzed dehydrogenation of 3-methylindole.

Skiles GL, Yost GS. Skiles GL, et al. Chem Res Toxicol. 1996 Jan-Feb;9(1):291-7. doi: 10.1021/tx9501187. Chem Res Toxicol. 1996. PMID: 8924606

7

Teratogenicity of carbamazepine-10, 11-epoxide and oxcarbazepine in the SWV mouse.

Bennett GD, Amore BM, Finnell RH, Wlodarczyk B, Kalhorn TF, Skiles GL, Nelson SD, Slattery JT. Bennett GD, et al. Among authors: skiles gl. J Pharmacol Exp Ther. 1996 Dec;279(3):1237-42. J Pharmacol Exp Ther. 1996. PMID: 8968346

8

Modeling, prediction, and in vitro in vivo correlation of CYP3A4 induction.

Shou M, Hayashi M, Pan Y, Xu Y, Morrissey K, Xu L, Skiles GL. Shou M, et al. Among authors: skiles gl. Drug Metab Dispos. 2008 Nov;36(11):2355-70. doi: 10.1124/dmd.108.020602. Epub 2008 Jul 31. Drug Metab Dispos. 2008. PMID: 18669588

9

Characterization of carbamazepine metabolism in a mouse model of carbamazepine teratogenicity.

Amore BM, Kalhorn TF, Skiles GL, Hunter AP, Bennett GD, Finnell RH, Nelson SD, Slattery JT. Amore BM, et al. Among authors: skiles gl. Drug Metab Dispos. 1997 Aug;25(8):953-62. Drug Metab Dispos. 1997. PMID: 9280403

10

Evidence supporting the formation of 2,3-epoxy-3-methylindoline: a reactive intermediate of the pneumotoxin 3-methylindole.

Skordos KW, Skiles GL, Laycock JD, Lanza DL, Yost GS. Skordos KW, et al. Among authors: skiles gl. Chem Res Toxicol. 1998 Jul;11(7):741-9. doi: 10.1021/tx9702087. Chem Res Toxicol. 1998. PMID: 9671536

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