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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1976 1
1977 4
1978 1
1979 7
1980 4
1981 4
1982 9
1983 4
1984 7
1985 6
1986 7
1987 10
1988 3
1989 6
1990 8
1991 5
1992 3
1993 6
1994 4
1995 4
1996 8
1997 5
1998 3
1999 7
2000 4
2001 11
2002 11
2003 9
2004 11
2005 9
2006 9
2007 13
2008 11
2009 15
2010 15
2011 18
2012 15
2013 13
2014 12
2015 13
2016 10
2017 3
2018 13
2019 3
2020 5
2021 3
2022 1
2023 0
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Search Results

329 results
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Page 1
Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.
Sykes DB, Kfoury YS, Mercier FE, Wawer MJ, Law JM, Haynes MK, Lewis TA, Schajnovitz A, Jain E, Lee D, Meyer H, Pierce KA, Tolliday NJ, Waller A, Ferrara SJ, Eheim AL, Stoeckigt D, Maxcy KL, Cobert JM, Bachand J, Szekely BA, Mukherjee S, Sklar LA, Kotz JD, Clish CB, Sadreyev RI, Clemons PA, Janzer A, Schreiber SL, Scadden DT. Sykes DB, et al. Among authors: sklar la. Cell. 2016 Sep 22;167(1):171-186.e15. doi: 10.1016/j.cell.2016.08.057. Epub 2016 Sep 15. Cell. 2016. PMID: 27641501 Free PMC article.
RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia.
Matthijssens F, Sharma ND, Nysus M, Nickl CK, Kang H, Perez DR, Lintermans B, Van Loocke W, Roels J, Peirs S, Demoen L, Pieters T, Reunes L, Lammens T, De Moerloose B, Van Nieuwerburgh F, Deforce DL, Cheung LC, Kotecha RS, Risseeuw MD, Van Calenbergh S, Takarada T, Yoneda Y, van Delft FW, Lock RB, Merkley SD, Chigaev A, Sklar LA, Mullighan CG, Loh ML, Winter SS, Hunger SP, Goossens S, Castillo EF, Ornatowski W, Van Vlierberghe P, Matlawska-Wasowska K. Matthijssens F, et al. Among authors: sklar la. J Clin Invest. 2021 Mar 15;131(6):e141566. doi: 10.1172/JCI141566. J Clin Invest. 2021. PMID: 33555272 Free PMC article.
Clioquinol: To harm or heal.
Perez DR, Sklar LA, Chigaev A. Perez DR, et al. Among authors: sklar la. Pharmacol Ther. 2019 Jul;199:155-163. doi: 10.1016/j.pharmthera.2019.03.009. Epub 2019 Mar 18. Pharmacol Ther. 2019. PMID: 30898518 Free PMC article. Review.
Unexplored therapeutic opportunities in the human genome.
Oprea TI, Bologa CG, Brunak S, Campbell A, Gan GN, Gaulton A, Gomez SM, Guha R, Hersey A, Holmes J, Jadhav A, Jensen LJ, Johnson GL, Karlson A, Leach AR, Ma'ayan A, Malovannaya A, Mani S, Mathias SL, McManus MT, Meehan TF, von Mering C, Muthas D, Nguyen DT, Overington JP, Papadatos G, Qin J, Reich C, Roth BL, Schürer SC, Simeonov A, Sklar LA, Southall N, Tomita S, Tudose I, Ursu O, Vidovic D, Waller A, Westergaard D, Yang JJ, Zahoránszky-Köhalmi G. Oprea TI, et al. Among authors: sklar la. Nat Rev Drug Discov. 2018 May;17(5):317-332. doi: 10.1038/nrd.2018.14. Epub 2018 Mar 23. Nat Rev Drug Discov. 2018. PMID: 29472638 Free PMC article. Review.
Selective Bcl-2 Inhibitor Probes.
Zou J, Ardecky R, Pinkerton AB, Sergienko E, Su Y, Stonich D, Curpan RF, Simons PC, Zhai D, Diaz P, Young SM, Carter MB, Bologa GC, Oprea TI, Edwards BS, Satterhwait AC, Mangravita-Novo A, Vicchiarelli M, McAnally D, Smith LH, Diwan J, Chung TDY, Reed JC, Sklar LA. Zou J, et al. Among authors: sklar la. 2011 Oct 31 [updated 2013 Feb 28]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2011 Oct 31 [updated 2013 Feb 28]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 23658956 Free Books & Documents. Review.
Targeting efflux pumps to overcome antifungal drug resistance.
Holmes AR, Cardno TS, Strouse JJ, Ivnitski-Steele I, Keniya MV, Lackovic K, Monk BC, Sklar LA, Cannon RD. Holmes AR, et al. Among authors: sklar la. Future Med Chem. 2016 Aug;8(12):1485-501. doi: 10.4155/fmc-2016-0050. Epub 2016 Jul 27. Future Med Chem. 2016. PMID: 27463566 Free PMC article. Review.
Far away from the lamppost.
Oprea TI, Jan L, Johnson GL, Roth BL, Ma'ayan A, Schürer S, Shoichet BK, Sklar LA, McManus MT. Oprea TI, et al. Among authors: sklar la. PLoS Biol. 2018 Dec 11;16(12):e3000067. doi: 10.1371/journal.pbio.3000067. eCollection 2018 Dec. PLoS Biol. 2018. PMID: 30532236 Free PMC article.
Flow Cytometry: Impact on Early Drug Discovery.
Edwards BS, Sklar LA. Edwards BS, et al. Among authors: sklar la. J Biomol Screen. 2015 Jul;20(6):689-707. doi: 10.1177/1087057115578273. Epub 2015 Mar 24. J Biomol Screen. 2015. PMID: 25805180 Free PMC article. Review.
329 results