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Year Number of Results
2010 1
2011 1
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2020 2
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2023 1
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Page 1
Targeting arginase-1 exerts antitumor effects in multiple myeloma and mitigates bortezomib-induced cardiotoxicity.
Ramji K, Grzywa TM, Sosnowska A, Paterek A, Okninska M, Pilch Z, Barankiewicz J, Garbicz F, Borg K, Bany-Laszewicz U, Zerrouqi A, Pyrzynska B, Rodziewicz-Lurzynska A, Papiernik D, Sklepkiewicz P, Kedzierska H, Staruch A, Sadowski R, Ciepiela O, Lech-Maranda E, Juszczynski P, Mackiewicz U, Maczewski M, Nowis D, Golab J. Ramji K, et al. Among authors: sklepkiewicz p. Sci Rep. 2022 Nov 16;12(1):19660. doi: 10.1038/s41598-022-24137-1. Sci Rep. 2022. PMID: 36385153 Free PMC article.
Trinucleotide mRNA Cap Analogue N6-Benzylated at the Site of Posttranscriptional m6Am Mark Facilitates mRNA Purification and Confers Superior Translational Properties In Vitro and In Vivo.
Warminski M, Trepkowska E, Smietanski M, Sikorski PJ, Baranowski MR, Bednarczyk M, Kedzierska H, Majewski B, Mamot A, Papiernik D, Popielec A, Serwa RA, Shimanski BA, Sklepkiewicz P, Sklucka M, Sokolowska O, Spiewla T, Toczydlowska-Socha D, Warminska Z, Wolosewicz K, Zuberek J, Mugridge JS, Nowis D, Golab J, Jemielity J, Kowalska J. Warminski M, et al. Among authors: sklepkiewicz p. J Am Chem Soc. 2024 Mar 27;146(12):8149-8163. doi: 10.1021/jacs.3c12629. Epub 2024 Mar 5. J Am Chem Soc. 2024. PMID: 38442005 Free PMC article.
Inhibition of CHIT1 as a novel therapeutic approach in idiopathic pulmonary fibrosis.
Sklepkiewicz P, Dymek BA, Mlacki M, Koralewski R, Mazur M, Nejman-Gryz P, Korur S, Zagozdzon A, Rymaszewska A, von der Thüsen JH, Siwińska AM, Güner NC, Cheda Ł, Paplinska-Goryca M, Proboszcz M, van den Bosch TPP, Górska K, Golab J, Kamiński RM, Krenke R, Golebiowski A, Dzwonek K, Dobrzanski P. Sklepkiewicz P, et al. Eur J Pharmacol. 2022 Mar 15;919:174792. doi: 10.1016/j.ejphar.2022.174792. Epub 2022 Feb 2. Eur J Pharmacol. 2022. PMID: 35122869 Free article.
Pharmacological Inhibition of Chitotriosidase (CHIT1) as a Novel Therapeutic Approach for Sarcoidosis.
Dymek B, Sklepkiewicz P, Mlacki M, Güner NC, Nejman-Gryz P, Drzewicka K, Przysucha N, Rymaszewska A, Paplinska-Goryca M, Zagozdzon A, Proboszcz M, Krzemiński Ł, von der Thüsen JH, Górska K, Dzwonek K, Zasłona Z, Dobrzanski P, Krenke R. Dymek B, et al. Among authors: sklepkiewicz p. J Inflamm Res. 2022 Sep 29;15:5621-5634. doi: 10.2147/JIR.S378357. eCollection 2022. J Inflamm Res. 2022. PMID: 36199746 Free PMC article.
Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase.
Andryianau G, Kowalski M, Piotrowicz MC, Rajkiewicz AA, Dymek B, Sklepkiewicz PL, Pluta E, Stefaniak F, Czestkowski W, Olejniczak S, Mazur M, Niedziejko P, Koralewski R, Matyszewski K, Gruza M, Zagozdzon A, Salamon M, Rymaszewska A, Welzer M, Dzwonek K, Golab J, Olczak J, Bartoszewicz A, Golebiowski A. Andryianau G, et al. Among authors: sklepkiewicz pl. ACS Med Chem Lett. 2020 Apr 24;11(6):1228-1235. doi: 10.1021/acsmedchemlett.0c00092. eCollection 2020 Jun 11. ACS Med Chem Lett. 2020. PMID: 32551005 Free PMC article.
Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma.
Mazur M, Olczak J, Olejniczak S, Koralewski R, Czestkowski W, Jedrzejczak A, Golab J, Dzwonek K, Dymek B, Sklepkiewicz PL, Zagozdzon A, Noonan T, Mahboubi K, Conway B, Sheeler R, Beckett P, Hungerford WM, Podjarny A, Mitschler A, Cousido-Siah A, Fadel F, Golebiowski A. Mazur M, et al. Among authors: sklepkiewicz pl. J Med Chem. 2018 Feb 8;61(3):695-710. doi: 10.1021/acs.jmedchem.7b01051. Epub 2018 Jan 11. J Med Chem. 2018. PMID: 29283260
Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases.
Mazur M, Dymek B, Koralewski R, Sklepkiewicz P, Olejniczak S, Mazurkiewicz M, Piotrowicz M, Salamon M, Jędrzejczak K, Zagozdzon A, Czestkowski W, Matyszewski K, Borek B, Bartoszewicz A, Pluta E, Rymaszewska A, Mozga W, Stefaniak F, Dobrzański P, Dzwonek K, Golab J, Golebiowski A, Olczak J. Mazur M, et al. Among authors: sklepkiewicz p. J Med Chem. 2019 Aug 8;62(15):7126-7145. doi: 10.1021/acs.jmedchem.9b00681. Epub 2019 Jul 23. J Med Chem. 2019. PMID: 31291098
Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis.
Koralewski R, Dymek B, Mazur M, Sklepkiewicz P, Olejniczak S, Czestkowski W, Matyszewski K, Andryianau G, Niedziejko P, Kowalski M, Gruza M, Borek B, Jedrzejczak K, Bartoszewicz A, Pluta E, Rymaszewska A, Kania M, Rejczak T, Piasecka S, Mlacki M, Mazurkiewicz M, Piotrowicz M, Salamon M, Zagozdzon A, Napiorkowska-Gromadzka A, Bartlomiejczak A, Mozga W, Dobrzański P, Dzwonek K, Golab J, Nowotny M, Olczak J, Golebiowski A. Koralewski R, et al. Among authors: sklepkiewicz p. J Med Chem. 2020 Dec 24;63(24):15527-15540. doi: 10.1021/acs.jmedchem.0c01179. Epub 2020 Oct 20. J Med Chem. 2020. PMID: 33078933
15 results