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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2005 2
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2008 2
2009 2
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2011 3
2012 4
2013 4
2016 4
2017 3
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2020 5
2021 5
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63 results

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Page 1
Emerging therapeutic opportunities for integrin inhibitors.
Slack RJ, Macdonald SJF, Roper JA, Jenkins RG, Hatley RJD. Slack RJ, et al. Nat Rev Drug Discov. 2022 Jan;21(1):60-78. doi: 10.1038/s41573-021-00284-4. Epub 2021 Sep 17. Nat Rev Drug Discov. 2022. PMID: 34535788 Free PMC article. Review.
Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis.
Hirani N, MacKinnon AC, Nicol L, Ford P, Schambye H, Pedersen A, Nilsson UJ, Leffler H, Sethi T, Tantawi S, Gravelle L, Slack RJ, Mills R, Karmakar U, Humphries D, Zetterberg F, Keeling L, Paul L, Molyneaux PL, Li F, Funston W, Forrest IA, Simpson AJ, Gibbons MA, Maher TM. Hirani N, et al. Among authors: slack rj. Eur Respir J. 2021 May 27;57(5):2002559. doi: 10.1183/13993003.02559-2020. Print 2021 May. Eur Respir J. 2021. PMID: 33214209 Free PMC article. Clinical Trial.
Galectin-3: therapeutic targeting in liver disease.
Mackinnon AC, Tonev D, Jacoby B, Pinzani M, Slack RJ. Mackinnon AC, et al. Among authors: slack rj. Expert Opin Ther Targets. 2023 Jul-Dec;27(9):779-791. doi: 10.1080/14728222.2023.2258280. Epub 2023 Sep 15. Expert Opin Ther Targets. 2023. PMID: 37705214 Free article. Review.
Defining the mechanism of galectin-3-mediated TGF-β1 activation and its role in lung fibrosis.
Calver JF, Parmar NR, Harris G, Lithgo RM, Stylianou P, Zetterberg FR, Gooptu B, Mackinnon AC, Carr SB, Borthwick LA, Scott DJ, Stewart ID, Slack RJ, Jenkins RG, John AE. Calver JF, et al. Among authors: slack rj. J Biol Chem. 2024 Jun;300(6):107300. doi: 10.1016/j.jbc.2024.107300. Epub 2024 Apr 18. J Biol Chem. 2024. PMID: 38641066 Free PMC article.
Discovery of Selective and Orally Available Galectin-1 Inhibitors.
Zetterberg FR, Diehl C, Håkansson M, Kahl-Knutson B, Leffler H, Nilsson UJ, Peterson K, Roper JA, Slack RJ. Zetterberg FR, et al. Among authors: slack rj. J Med Chem. 2023 Dec 28;66(24):16980-16990. doi: 10.1021/acs.jmedchem.3c01787. Epub 2023 Dec 7. J Med Chem. 2023. PMID: 38059452
Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis.
John AE, Graves RH, Pun KT, Vitulli G, Forty EJ, Mercer PF, Morrell JL, Barrett JW, Rogers RF, Hafeji M, Bibby LI, Gower E, Morrison VS, Man Y, Roper JA, Luckett JC, Borthwick LA, Barksby BS, Burgoyne RA, Barnes R, Le J, Flint DJ, Pyne S, Habgood A, Organ LA, Joseph C, Edwards-Pritchard RC, Maher TM, Fisher AJ, Gudmann NS, Leeming DJ, Chambers RC, Lukey PT, Marshall RP, Macdonald SJF, Jenkins RG, Slack RJ. John AE, et al. Among authors: slack rj. Nat Commun. 2020 Sep 16;11(1):4659. doi: 10.1038/s41467-020-18397-6. Nat Commun. 2020. PMID: 32938936 Free PMC article.
63 results