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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 4
2002 12
2003 28
2004 28
2005 32
2006 27
2007 27
2008 31
2009 32
2010 37
2011 34
2012 31
2013 29
2014 46
2015 36
2016 46
2017 39
2018 23
2019 23
2020 19
2021 22
2022 10
2023 12
2024 18
2025 17
2026 1

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577 results

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Page 1
A gut-brain neural circuit for nutrient sensory transduction.
Kaelberer MM, Buchanan KL, Klein ME, Barth BB, Montoya MM, Shen X, Bohórquez DV. Kaelberer MM, et al. Science. 2018 Sep 21;361(6408):eaat5236. doi: 10.1126/science.aat5236. Science. 2018. PMID: 30237325 Free PMC article.
Endothelial TFEB signaling-mediated autophagic disturbance initiates microglial activation and cognitive dysfunction.
Lu Y, Chen X, Liu X, Shi Y, Wei Z, Feng L, Jiang Q, Ye W, Sasaki T, Fukunaga K, Ji Y, Han F, Lu YM. Lu Y, et al. Autophagy. 2023 Jun;19(6):1803-1820. doi: 10.1080/15548627.2022.2162244. Epub 2023 Jan 1. Autophagy. 2023. PMID: 36588318 Free PMC article.
Our results suggest the reversal of TFEB nuclear translocation may provide a novel therapeutic approach to prevent symptoms of cognitive dysfunction during clinical use of bortezomib.Abbreviations: AAV: adeno-associated virus; BBB: blood-brain barrier; BTZ: bortezomib; DG: digoxi …
Our results suggest the reversal of TFEB nuclear translocation may provide a novel therapeutic approach to prevent symptoms of cognitive dys …
Identification of early Alzheimer's disease subclass and signature genes based on PANoptosis genes.
Wang W, Lu J, Pan N, Zhang H, Dai J, Li J, Chi C, Zhang L, Wang L, Zhang M. Wang W, et al. Front Immunol. 2024 Nov 22;15:1462003. doi: 10.3389/fimmu.2024.1462003. eCollection 2024. Front Immunol. 2024. PMID: 39650656 Free PMC article.
CONCLUSION: In summary, we identified two subtypes, including the AD early synaptic abnormality subtype as well as the immune-metabolic subtype. Additionally, ten hub genes, SLC17A7, SNAP25, GAD1, SLC17A6, SLC32A1, PVALB, SYP, GRIN2A, SLC12A5, and SYN2, were identified as …
CONCLUSION: In summary, we identified two subtypes, including the AD early synaptic abnormality subtype as well as the immune-metabolic subt …
Genetic variation in SLC17A7 promoter associated with response to sport-related concussions.
Madura SA, McDevitt JK, Tierney RT, Mansell JL, Hayes DJ, Gaughan JP, Krynetskiy E. Madura SA, et al. Brain Inj. 2016;30(7):908-13. doi: 10.3109/02699052.2016.1146958. Epub 2016 Mar 30. Brain Inj. 2016. PMID: 27029226
OBJECTIVE: To determine the association of the single nucleotide polymorphism (SNP) rs74174284 within SLC17A7 promoter with concussion severity or duration. DESIGN: A between-subjects design was utilized. ...CONCLUSIONS: This study was the first to demonstrate an associati …
OBJECTIVE: To determine the association of the single nucleotide polymorphism (SNP) rs74174284 within SLC17A7 promoter with concussio …
SLC17A7 gene may be the indicator of selective serotonin reuptake inhibitor treatment response in the Chinese Han population.
Li X, Yu T, Huang X, Cao Y, Li X, Liu B, Yang F, Li W, Zhao X, Feng G, Zhang X, Dong Z, Lin Y, Li X, He L, Sun X, He G. Li X, et al. J Clin Psychopharmacol. 2014 Jun;34(3):331-6. doi: 10.1097/JCP.0000000000000119. J Clin Psychopharmacol. 2014. PMID: 24743714
The vesicular glutamate transporter 1 coded by SLC17A7 gene has been reported associated with MDD. According to its role in glutamate transmission, it is reasonable to consider it as a potential pharmacogenetic candidate in SSRI treatment. ...Our results suggest that genet …
The vesicular glutamate transporter 1 coded by SLC17A7 gene has been reported associated with MDD. According to its role in glutamate …
Adult-onset deactivation of autophagy leads to loss of synapse homeostasis and cognitive impairment, with implications for alzheimer disease.
Grosso Jasutkar H, Wasserlein EM, Ishola A, Litt N, Staniszewski A, Arancio O, Yamamoto A. Grosso Jasutkar H, et al. Autophagy. 2024 Nov;20(11):2540-2555. doi: 10.1080/15548627.2024.2368335. Epub 2024 Jul 1. Autophagy. 2024. PMID: 38949671 Free PMC article.
In the symptomatic APP PSEN1 double-transgenic mouse model of AD, we found that the impairment in autophagosome maturation coupled with diminished presence of discrete synaptic proteins in autophagosomes isolated from these mice, leading to the accumulation of one of these protei …
In the symptomatic APP PSEN1 double-transgenic mouse model of AD, we found that the impairment in autophagosome maturation coupled with dimi …
Genomic evolution reshapes cell-type diversification in the amniote brain.
Chen D, Zhuang Z, Huang M, Huang Y, Yan Y, Zhang Y, Lin Y, Jin X, Wang Y, Huang J, Xu W, Pan J, Wang H, Huang F, Liao K, Cheng M, Zhu Z, Bai Y, Niu Z, Zhang Z, Xiang Y, Wei X, Yang T, Zeng T, Dong Y, Lei Y, Sun Y, Wang J, Yang H, Sun Y, Cao G, Poo M, Liu L, Naumann RK, Xu C, Wang Z, Xu X, Liu S. Chen D, et al. Dev Cell. 2025 Jul 7;60(13):1900-1915.e5. doi: 10.1016/j.devcel.2025.04.014. Epub 2025 May 13. Dev Cell. 2025. PMID: 40367951
Birds predominantly express SLC17A6 in EX, whereas mammals express SLC17A7 in the neocortex and SLC17A6 elsewhere, possibly due to loss of function of SLC17A7 in birds. ...
Birds predominantly express SLC17A6 in EX, whereas mammals express SLC17A7 in the neocortex and SLC17A6 elsewhere, possibly due to lo …
Global analysis of H3K4me3 and H3K27me3 profiles in glioblastoma stem cells and identification of SLC17A7 as a bivalent tumor suppressor gene.
Lin B, Lee H, Yoon JG, Madan A, Wayner E, Tonning S, Hothi P, Schroeder B, Ulasov I, Foltz G, Hood L, Cobbs C. Lin B, et al. Oncotarget. 2015 Mar 10;6(7):5369-81. doi: 10.18632/oncotarget.3030. Oncotarget. 2015. PMID: 25749033 Free PMC article.
These bivalent genes are potential targets for inducing differentiation in glioblastoma (GBM) as a therapeutic approach. Finally, we identified SLC17A7 as a bivalent tumor suppressor gene in GBM, as it is down-regulated at both the protein and RNA levels in GBM tissues com …
These bivalent genes are potential targets for inducing differentiation in glioblastoma (GBM) as a therapeutic approach. Finally, we identif …
Investigation of brain structures and potential mechanisms associated with ADHD: Insights from Mendelian randomization and genetic analysis.
Hu X, Lin L, Wu Z. Hu X, et al. J Affect Disord. 2025 Jun 15;379:519-528. doi: 10.1016/j.jad.2025.03.024. Epub 2025 Mar 5. J Affect Disord. 2025. PMID: 40054538
PPI analysis pinpointed key proteins like SLC17A7, CAMK2A, and SST as critical hubs. CONCLUSION: This research confirms negative correlations between certain brain structures and ADHD and implicates neuroactive ligand-receptor interactions in its pathogenesis, enhancing ou …
PPI analysis pinpointed key proteins like SLC17A7, CAMK2A, and SST as critical hubs. CONCLUSION: This research confirms negative corr …
577 results