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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 1
1983 1
1987 1
1989 3
1991 1
1992 1
1993 3
1994 1
1996 1
1999 3
2005 1
2006 3
2007 1
2010 2
2011 1
2012 1
2013 3
2014 2
2015 1
2017 1
2018 2
2022 0
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32 results
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Page 1
Antagonists of CCR4 as immunomodulatory agents.
Purandare AV, Somerville JE. Purandare AV, et al. Among authors: somerville je. Curr Top Med Chem. 2006;6(13):1335-44. doi: 10.2174/15680266106061335. Curr Top Med Chem. 2006. PMID: 16918452 Review.
CD28 ligation increases macrophage suppression of T-cell proliferation.
Silberman D, Bucknum A, Bartlett T, Composto G, Kozlowski M, Walker A, Werda A, Cua J, Sharpe AH, Somerville JE, Riggs JE. Silberman D, et al. Among authors: somerville je. Cell Mol Immunol. 2012 Jul;9(4):341-9. doi: 10.1038/cmi.2012.13. Epub 2012 Apr 23. Cell Mol Immunol. 2012. PMID: 22522653 Free PMC article.
Development of a Molecular Signature to Monitor Pharmacodynamic Responses Mediated by In Vivo Administration of Glucocorticoids.
Hu Y, Carman JA, Holloway D, Kansal S, Fan L, Goldstine C, Lee D, Somerville JE, Latek R, Townsend R, Johnsen A, Connolly S, Bandyopadhyay S, Shadick N, Weinblatt ME, Furie R, Nadler SG. Hu Y, et al. Among authors: somerville je. Arthritis Rheumatol. 2018 Aug;70(8):1331-1342. doi: 10.1002/art.40476. Epub 2018 Jul 12. Arthritis Rheumatol. 2018. PMID: 29534336 Free PMC article.
Discovery of potent and selective nonsteroidal indazolyl amide glucocorticoid receptor agonists.
Sheppeck JE 2nd, Gilmore JL, Xiao HY, Dhar TG, Nirschl D, Doweyko AM, Sack JS, Corbett MJ, Malley MF, Gougoutas JZ, Mckay L, Cunningham MD, Habte SF, Dodd JH, Nadler SG, Somerville JE, Barrish JC. Sheppeck JE 2nd, et al. Among authors: somerville je. Bioorg Med Chem Lett. 2013 Oct 1;23(19):5442-7. doi: 10.1016/j.bmcl.2013.06.089. Epub 2013 Jul 9. Bioorg Med Chem Lett. 2013. PMID: 23953070
Improving the pharmacokinetic and CYP inhibition profiles of azaxanthene-based glucocorticoid receptor modulators-identification of (S)-5-(2-(9-fluoro-2-(4-(2-hydroxypropan-2-yl)phenyl)-5H-chromeno[2,3-b]pyridin-5-yl)-2-methylpropanamido)-N-(tetrahydro-2H-pyran-4-yl)-1,3,4-thiadiazole-2-carboxamide (BMS-341).
Yang MG, Dhar TG, Xiao Z, Xiao HY, Duan JJ, Jiang B, Galella MA, Cunningham M, Wang J, Habte S, Shuster D, McIntyre KW, Carman J, Holloway DA, Somerville JE, Nadler SG, Salter-Cid L, Barrish JC, Weinstein DS. Yang MG, et al. Among authors: somerville je. J Med Chem. 2015 May 28;58(10):4278-90. doi: 10.1021/acs.jmedchem.5b00257. Epub 2015 May 7. J Med Chem. 2015. PMID: 25905990
Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity.
Gong H, Weinstein DS, Lu Z, Duan JJ, Stachura S, Haque L, Karmakar A, Hemagiri H, Raut DK, Gupta AK, Khan J, Camac D, Sack JS, Pudzianowski A, Wu DR, Yarde M, Shen DR, Borowski V, Xie JH, Sun H, D'Arienzo C, Dabros M, Galella MA, Wang F, Weigelt CA, Zhao Q, Foster W, Somerville JE, Salter-Cid LM, Barrish JC, Carter PH, Dhar TGM. Gong H, et al. Among authors: somerville je. Bioorg Med Chem Lett. 2018 Jan 15;28(2):85-93. doi: 10.1016/j.bmcl.2017.12.006. Epub 2017 Dec 5. Bioorg Med Chem Lett. 2018. PMID: 29233651
Dimethyl-diphenyl-propanamide derivatives as nonsteroidal dissociated glucocorticoid receptor agonists.
Yang BV, Weinstein DS, Doweyko LM, Gong H, Vaccaro W, Huynh T, Xiao HY, Doweyko AM, McKay L, Holloway DA, Somerville JE, Habte S, Cunningham M, McMahon M, Townsend R, Shuster D, Dodd JH, Nadler SG, Barrish JC. Yang BV, et al. Among authors: somerville je. J Med Chem. 2010 Dec 9;53(23):8241-51. doi: 10.1021/jm100957a. Epub 2010 Nov 12. J Med Chem. 2010. PMID: 21073190
32 results