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The following term was not found in PubMed: nooraee-motlagh
Page 1
Did you mean soraya nouraei motlagh (10 results)?
Efficacy and Safety of Mirvetuximab Soravtansine in Patients With Platinum-Resistant Ovarian Cancer With High Folate Receptor Alpha Expression: Results From the SORAYA Study.
Matulonis UA, Lorusso D, Oaknin A, Pignata S, Dean A, Denys H, Colombo N, Van Gorp T, Konner JA, Marin MR, Harter P, Murphy CG, Wang J, Noble E, Esteves B, Method M, Coleman RL. Matulonis UA, et al. J Clin Oncol. 2023 May 1;41(13):2436-2445. doi: 10.1200/JCO.22.01900. Epub 2023 Jan 30. J Clin Oncol. 2023. PMID: 36716407 Free PMC article. Clinical Trial.
Mirvetuximab soravtansine (MIRV) is an antibody-drug conjugate targeting folate receptor alpha (FRalpha). SORAYA is a single-arm, phase II study evaluating efficacy and safety of MIRV in patients with PROC. METHODS: SORAYA enrolled FRalpha-high patients with PROC wh …
Mirvetuximab soravtansine (MIRV) is an antibody-drug conjugate targeting folate receptor alpha (FRalpha). SORAYA is a single-arm, pha …
Antibody-Drug Conjugates in Gynecologic Cancer.
Karpel HC, Powell SS, Pothuri B. Karpel HC, et al. Am Soc Clin Oncol Educ Book. 2023 May;43:e390772. doi: 10.1200/EDBK_390772. Am Soc Clin Oncol Educ Book. 2023. PMID: 37229642 Free article. Review.
In ovarian cancer, mirvetuximab soravtansine, an ADC targeting alpha-folate receptor (FRalpha), received US Food and Drug Administration (FDA) accelerated approval in November 2022 after data from the single-arm phase III SORAYA trial. A second ADC targeting FRalpha, STRO- …
In ovarian cancer, mirvetuximab soravtansine, an ADC targeting alpha-folate receptor (FRalpha), received US Food and Drug Administration (FD …
Strategies for prevention and management of ocular events occurring with mirvetuximab soravtansine.
Hendershot A, Slabaugh M, Riaz KM, Moore KN, O'Malley DM, Matulonis U, Konecny GE. Hendershot A, et al. Gynecol Oncol Rep. 2023 Feb 28;47:101155. doi: 10.1016/j.gore.2023.101155. eCollection 2023 Jun. Gynecol Oncol Rep. 2023. PMID: 37102083 Free PMC article. Review.
Pooled safety analysis of 464 MIRV-treated patients across 3 trials, including the phase 2 SORAYA study, found that 50% of patients had 1 ocular AEs of interest (AEIs) of blurred vision or keratopathy, the majority being grade 2. ...
Pooled safety analysis of 464 MIRV-treated patients across 3 trials, including the phase 2 SORAYA study, found that 50% of patients h …
Mirvetuximab soravtansine in folate receptor alpha (FRalpha)-high platinum-resistant ovarian cancer: final overall survival and post hoc sequence of therapy subgroup results from the SORAYA trial.
Coleman RL, Lorusso D, Oaknin A, Cecere SC, Denys H, Colombo N, van Gorp T, Konner JA, Romeo Marin M, Harter P, Murphy C, Wang Y, Esteves B, Method M, Matulonis U. Coleman RL, et al. Int J Gynecol Cancer. 2024 Aug 5;34(8):1119-1125. doi: 10.1136/ijgc-2024-005401. Int J Gynecol Cancer. 2024. PMID: 38858103 Free PMC article. Clinical Trial.
OBJECTIVE: The single-arm, phase II SORAYA trial (NCT04296890) of mirvetuximab soravtansine-gynx in folate receptor alpha (FRalpha)-high platinum-resistant ovarian cancer (n=105 (efficacy-evaluable)) met its primary endpoint with an objective response rate of 32.4% (95% CI …
OBJECTIVE: The single-arm, phase II SORAYA trial (NCT04296890) of mirvetuximab soravtansine-gynx in folate receptor alpha (FRalpha)-h …
Mirvetuximab soravtansine: current and future applications.
Kong B, Zheng W. Kong B, et al. J Hematol Oncol. 2025 Mar 18;18(1):33. doi: 10.1186/s13045-025-01686-2. J Hematol Oncol. 2025. PMID: 40102896 Free PMC article. Review.
Mirvetuximab soravtansine (MIRV), an antibody-drug conjugate targeting folate receptor alpha (FRalpha), has demonstrated promising efficacy in platinum-resistant OEC, particularly in high FRalpha-expressing populations, as evidenced by key clinical trials such as FORWARD I, FORWA …
Mirvetuximab soravtansine (MIRV), an antibody-drug conjugate targeting folate receptor alpha (FRalpha), has demonstrated promising efficacy …
Harnessing intestinal tryptophan catabolism to relieve atherosclerosis in mice.
Chajadine M, Laurans L, Radecke T, Mouttoulingam N, Al-Rifai R, Bacquer E, Delaroque C, Rytter H, Bredon M, Knosp C, Vilar J, Fontaine C, Suffee N, Vandestienne M, Esposito B, Dairou J, Launay JM, Callebert J, Tedgui A, Ait-Oufella H, Sokol H, Chassaing B, Taleb S. Chajadine M, et al. Nat Commun. 2024 Jul 29;15(1):6390. doi: 10.1038/s41467-024-50807-x. Nat Commun. 2024. PMID: 39080345 Free PMC article.
Dendrimer Prodrugs.
da Silva Santos S, Igne Ferreira E, Giarolla J. da Silva Santos S, et al. Molecules. 2016 May 31;21(6):686. doi: 10.3390/molecules21060686. Molecules. 2016. PMID: 27258239 Free PMC article. Review.
Niacin.
Djadjo S, Bajaj T. Djadjo S, et al. 2023 Mar 20. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. 2023 Mar 20. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 31082080 Free Books & Documents.
Treatment of hypertension in patients 80 years of age or older.
Beckett NS, Peters R, Fletcher AE, Staessen JA, Liu L, Dumitrascu D, Stoyanovsky V, Antikainen RL, Nikitin Y, Anderson C, Belhani A, Forette F, Rajkumar C, Thijs L, Banya W, Bulpitt CJ; HYVET Study Group. Beckett NS, et al. N Engl J Med. 2008 May 1;358(18):1887-98. doi: 10.1056/NEJMoa0801369. Epub 2008 Mar 31. N Engl J Med. 2008. PMID: 18378519 Free article. Clinical Trial.
Antibody-Drug Conjugates in Gynecologic Cancers.
Anastasio MK, Shuey S, Davidson BA. Anastasio MK, et al. Curr Treat Options Oncol. 2024 Jan;25(1):1-19. doi: 10.1007/s11864-023-01166-0. Epub 2024 Jan 3. Curr Treat Options Oncol. 2024. PMID: 38172449 Review.
Mirvetuximab soravtansine targets folate receptor alpha and is approved for use in patients with folate receptor alpha-positive, platinum-resistant, epithelial ovarian cancer based on results from the SORAYA trial. While there are no FDA-approved ADCs for the treatment of …
Mirvetuximab soravtansine targets folate receptor alpha and is approved for use in patients with folate receptor alpha-positive, platinum-re …
460 results