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Page 1
Understanding prion structure and conversion.
Spagnolli G, Requena JR, Biasini E. Spagnolli G, et al. Prog Mol Biol Transl Sci. 2020;175:19-30. doi: 10.1016/bs.pmbts.2020.07.005. Epub 2020 Sep 11. Prog Mol Biol Transl Sci. 2020. PMID: 32958233 Review.
The cellular prion protein beyond prion diseases.
Manni G, Lewis V, Senesi M, Spagnolli G, Fallarino F, Collins SJ, Mouillet-Richard S, Biasini E. Manni G, et al. Among authors: spagnolli g. Swiss Med Wkly. 2020 Apr 24;150:w20222. doi: 10.4414/smw.2020.20222. eCollection 2020 Apr 20. Swiss Med Wkly. 2020. PMID: 32330284 Free article. Review.
Ok Google, how could I design therapeutics against prion diseases?
Rigoli M, Spagnolli G, Faccioli P, Requena JR, Biasini E. Rigoli M, et al. Among authors: spagnolli g. Curr Opin Pharmacol. 2019 Feb;44:39-45. doi: 10.1016/j.coph.2019.03.015. Epub 2019 May 3. Curr Opin Pharmacol. 2019. PMID: 31059982 Review.
Modeling PrPSc Generation Through Deformed Templating.
Spagnolli G, Rigoli M, Novi Inverardi G, Codeseira YB, Biasini E, Requena JR. Spagnolli G, et al. Front Bioeng Biotechnol. 2020 Oct 6;8:590501. doi: 10.3389/fbioe.2020.590501. eCollection 2020. Front Bioeng Biotechnol. 2020. PMID: 33123520 Free PMC article.
All-atom simulation of the HET-s prion replication.
Terruzzi L, Spagnolli G, Boldrini A, Requena JR, Biasini E, Faccioli P. Terruzzi L, et al. Among authors: spagnolli g. PLoS Comput Biol. 2020 Sep 18;16(9):e1007922. doi: 10.1371/journal.pcbi.1007922. eCollection 2020 Sep. PLoS Comput Biol. 2020. PMID: 32946455 Free PMC article.
All-atom calculation of protein free-energy profiles.
Orioli S, Ianeselli A, Spagnolli G, Faccioli P. Orioli S, et al. Among authors: spagnolli g. J Chem Phys. 2017 Oct 21;147(15):152724. doi: 10.1063/1.5006039. J Chem Phys. 2017. PMID: 29055321
Pharmacological inactivation of the prion protein by targeting a folding intermediate.
Spagnolli G, Massignan T, Astolfi A, Biggi S, Rigoli M, Brunelli P, Libergoli M, Ianeselli A, Orioli S, Boldrini A, Terruzzi L, Bonaldo V, Maietta G, Lorenzo NL, Fernandez LC, Codeseira YB, Tosatto L, Linsenmeier L, Vignoli B, Petris G, Gasparotto D, Pennuto M, Guella G, Canossa M, Altmeppen HC, Lolli G, Biressi S, Pastor MM, Requena JR, Mancini I, Barreca ML, Faccioli P, Biasini E. Spagnolli G, et al. Commun Biol. 2021 Jan 12;4(1):62. doi: 10.1038/s42003-020-01585-x. Commun Biol. 2021. PMID: 33437023 Free PMC article.
24 results