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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2010 1
2011 1
2012 3
2013 1
2014 1
2015 3
2017 1
2018 1
2019 6
2020 2
2021 1
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19 results
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Page 1
De novo design of potent and selective mimics of IL-2 and IL-15.
Silva DA, Yu S, Ulge UY, Spangler JB, Jude KM, Labão-Almeida C, Ali LR, Quijano-Rubio A, Ruterbusch M, Leung I, Biary T, Crowley SJ, Marcos E, Walkey CD, Weitzner BD, Pardo-Avila F, Castellanos J, Carter L, Stewart L, Riddell SR, Pepper M, Bernardes GJL, Dougan M, Garcia KC, Baker D. Silva DA, et al. Among authors: spangler jb. Nature. 2019 Jan;565(7738):186-191. doi: 10.1038/s41586-018-0830-7. Epub 2019 Jan 9. Nature. 2019. PMID: 30626941 Free PMC article.
Interleukin-2 activity can be fine tuned with engineered receptor signaling clamps.
Mitra S, Ring AM, Amarnath S, Spangler JB, Li P, Ju W, Fischer S, Oh J, Spolski R, Weiskopf K, Kohrt H, Foley JE, Rajagopalan S, Long EO, Fowler DH, Waldmann TA, Garcia KC, Leonard WJ. Mitra S, et al. Among authors: spangler jb. Immunity. 2015 May 19;42(5):826-38. doi: 10.1016/j.immuni.2015.04.018. Immunity. 2015. PMID: 25992859 Free PMC article.
Weaponizing T-cell receptors through molecular engineering.
Leonard EK, Leff MI, Spangler JB. Leonard EK, et al. Among authors: spangler jb. J Biol Chem. 2019 Apr 12;294(15):5805-5806. doi: 10.1074/jbc.H119.008479. J Biol Chem. 2019. PMID: 30979848 Free PMC article.
MammaPrint and BluePrint Molecular Diagnostics Using Targeted RNA Next-Generation Sequencing Technology.
Mittempergher L, Delahaye LJMJ, Witteveen AT, Spangler JB, Hassenmahomed F, Mee S, Mahmoudi S, Chen J, Bao S, Snel MHJ, Leidelmeijer S, Besseling N, Bergstrom Lucas A, Pabón-Peña C, Linn SC, Dreezen C, Wehkamp D, Chan BY, Bernards R, van 't Veer LJ, Glas AM. Mittempergher L, et al. Among authors: spangler jb. J Mol Diagn. 2019 Sep;21(5):808-823. doi: 10.1016/j.jmoldx.2019.04.007. Epub 2019 Jun 4. J Mol Diagn. 2019. PMID: 31173928 Free article.
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