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Year Number of Results
2019 2
2021 3
2022 3
2023 4
2024 2

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13 results

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Page 1
Oral Mucosal Organoids as a Potential Platform for Personalized Cancer Therapy.
Driehuis E, Kolders S, Spelier S, Lõhmussaar K, Willems SM, Devriese LA, de Bree R, de Ruiter EJ, Korving J, Begthel H, van Es JH, Geurts V, He GW, van Jaarsveld RH, Oka R, Muraro MJ, Vivié J, Zandvliet MMJM, Hendrickx APA, Iakobachvili N, Sridevi P, Kranenburg O, van Boxtel R, Kops GJPL, Tuveson DA, Peters PJ, van Oudenaarden A, Clevers H. Driehuis E, et al. Among authors: spelier s. Cancer Discov. 2019 Jul;9(7):852-871. doi: 10.1158/2159-8290.CD-18-1522. Epub 2019 May 3. Cancer Discov. 2019. PMID: 31053628
FDA-approved drug screening in patient-derived organoids demonstrates potential of drug repurposing for rare cystic fibrosis genotypes.
de Poel E, Spelier S, Hagemeijer MC, van Mourik P, Suen SWF, Vonk AM, Brunsveld JE, Ithakisiou GN, Kruisselbrink E, Oppelaar H, Berkers G, de Winter de Groot KM, Heida-Michel S, Jans SR, van Panhuis H, Bakker M, van der Meer R, Roukema J, Dompeling E, Weersink EJM, Koppelman GH, Blaazer AR, Muijlwijk-Koezen JE, van der Ent CK, Beekman JM. de Poel E, et al. Among authors: spelier s. J Cyst Fibros. 2023 May;22(3):548-559. doi: 10.1016/j.jcf.2023.03.004. Epub 2023 May 3. J Cyst Fibros. 2023. PMID: 37147251
Mutation-specific reporter for optimization and enrichment of prime editing.
Schene IF, Joore IP, Baijens JHL, Stevelink R, Kok G, Shehata S, Ilcken EF, Nieuwenhuis ECM, Bolhuis DP, van Rees RCM, Spelier SA, van der Doef HPJ, Beekman JM, Houwen RHJ, Nieuwenhuis EES, Fuchs SA. Schene IF, et al. Among authors: spelier sa. Nat Commun. 2022 Mar 1;13(1):1028. doi: 10.1038/s41467-022-28656-3. Nat Commun. 2022. PMID: 35232966 Free PMC article.
Functional Restoration of CFTR Nonsense Mutations in Intestinal Organoids.
de Poel E, Spelier S, Suen SWF, Kruisselbrink E, Graeber SY, Mall MA, Weersink EJM, van der Eerden MM, Koppelman GH, van der Ent CK, Beekman JM. de Poel E, et al. Among authors: spelier s. J Cyst Fibros. 2022 Mar;21(2):246-253. doi: 10.1016/j.jcf.2021.09.020. Epub 2021 Oct 17. J Cyst Fibros. 2022. PMID: 34666947 Free article.
Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia.
Amatngalim GD, Rodenburg LW, Aalbers BL, Raeven HH, Aarts EM, Sarhane D, Spelier S, Lefferts JW, Silva IA, Nijenhuis W, Vrendenbarg S, Kruisselbrink E, Brunsveld JE, van Drunen CM, Michel S, de Winter-de Groot KM, Heijerman HG, Kapitein LC, Amaral MD, van der Ent CK, Beekman JM. Amatngalim GD, et al. Among authors: spelier s. Life Sci Alliance. 2022 Aug 3;5(12):e202101320. doi: 10.26508/lsa.202101320. Life Sci Alliance. 2022. PMID: 35922154 Free PMC article.
Use of 2,6-diaminopurine as a potent suppressor of UGA premature stop codons in cystic fibrosis.
Leroy C, Spelier S, Essonghe NC, Poix V, Kong R, Gizzi P, Bourban C, Amand S, Bailly C, Guilbert R, Hannebique D, Persoons P, Arhant G, Prévotat A, Reix P, Hubert D, Gérardin M, Chamaillard M, Prevarskaya N, Rebuffat S, Shapovalov G, Beekman J, Lejeune F. Leroy C, et al. Among authors: spelier s. Mol Ther. 2023 Apr 5;31(4):970-985. doi: 10.1016/j.ymthe.2023.01.014. Epub 2023 Jan 14. Mol Ther. 2023. PMID: 36641622 Free PMC article.
13 results